{"id":"W2321754462","doi":"10.1021/bc2003814","title":"Degradable Thermoresponsive Nanogels for Protein Encapsulation and Controlled Release","year":2011,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Raft; Methacrylamide; Nanogel; Methacrylate; Copolymer; Polymerization; Polymer chemistry; Micelle; Chain transfer; Cationic polymerization; Reversible addition−fragmentation chain-transfer polymerization; Ethylene glycol; Chemical engineering; Drug delivery; Radical polymerization; Polymer; Organic chemistry; Acrylamide; Aqueous solution","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008116475,0.0002082723,0.0002681249,0.0000147292,0.000120101,0.00002743873,0.000107272,0.0001652454,0.0009434124],"category_scores_gemma":[0.0001516219,0.000185355,0.00008853929,0.00003959901,0.00007546451,0.0001174143,0.00002782037,0.00007066388,0.000005018108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002749929,"about_ca_system_score_gemma":0.00004350565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009007678,"about_ca_topic_score_gemma":3.7936e-7,"domain_scores_codex":[0.9990372,0.00001048117,0.0002888141,0.0003335387,0.00009401803,0.0002359506],"domain_scores_gemma":[0.9992803,0.00004936235,0.0002221352,0.0002571506,0.00008467535,0.0001063177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001193166,0.00005446019,0.00008126096,0.0001787642,0.00004087251,0.000002644316,0.0001475299,1.372979e-7,0.9943676,0.0001702085,0.00001371035,0.003749646],"study_design_scores_gemma":[0.002352497,0.00001413088,0.00007978077,0.00007459141,0.00004278417,0.00000615652,0.000137175,0.0002053519,0.9946589,0.0006963748,0.001496217,0.000236011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918975,0.0005338581,0.0006595472,0.00004722262,0.0000230825,0.0003646703,0.00008205736,0.00009076117,0.006301282],"genre_scores_gemma":[0.9925098,0.00003398824,0.0009737883,0.00003645628,0.0001231045,0.000497411,0.00008903974,0.00003743724,0.005698912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003513634,"threshold_uncertainty_score":0.9999698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061705629696206,"score_gpt":0.2142060199112404,"score_spread":0.1935889636142783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}