{"id":"W2321863683","doi":"10.1101/pdb.top086652","title":"Synthetic Genetic Arrays: Automation of Yeast Genetics","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Biology; Computational biology; Genome; Schizosaccharomyces pombe; Genetics; Saccharomyces cerevisiae; Genetic screen; Synthetic lethality; Model organism; Gene; Phenotype; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002598998,0.001235711,0.001255511,0.001397547,0.0005859816,0.001567389,0.002155274,0.0007719451,0.005743846],"category_scores_gemma":[0.002635437,0.001640288,0.0009631595,0.001201276,0.0007970192,0.0009098324,0.00164916,0.00261847,0.008239944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005967427,"about_ca_system_score_gemma":0.0006501148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007736787,"about_ca_topic_score_gemma":0.00130004,"domain_scores_codex":[0.9972128,0.0006313605,0.0002666842,0.0005193974,0.001235371,0.000134383],"domain_scores_gemma":[0.9987106,0.000387477,0.0001343184,0.0004809182,0.0001953839,0.00009126672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004992859,0.0001388882,0.0009941978,0.0007437011,0.0001072593,0.0002789314,0.0002660566,0.006882635,0.7788509,0.02221568,0.02311684,0.1659057],"study_design_scores_gemma":[0.000172171,0.0002600235,0.001452432,0.0001424615,0.00006032891,0.0009007379,0.00005821872,0.03503077,0.6738051,0.01694297,0.2709975,0.0001773691],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01096751,0.002270806,0.946771,0.0004193522,0.0004468164,0.0005372625,0.00494455,0.02534325,0.008299419],"genre_scores_gemma":[0.05241079,0.002864672,0.9242674,0.0003048088,0.0001026265,0.001997404,0.008045703,0.002812749,0.007193928],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.005743846,"threshold_uncertainty_score":0.01921505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963750717473389,"score_gpt":0.2856021384877231,"score_spread":0.2659646313129892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}