{"id":"W2321863683","doi":"10.1101/pdb.top086652","title":"Synthetic Genetic Arrays: Automation of Yeast Genetics","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Biology; Computational biology; Genome; Schizosaccharomyces pombe; Genetics; Saccharomyces cerevisiae; Genetic screen; Synthetic lethality; Model organism; Gene; Phenotype; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002151014,0.0001656868,0.0001673046,0.00007059811,0.00005235349,0.00002409636,0.0003655126,0.0001363108,0.00006437641],"category_scores_gemma":[0.0001356608,0.0001287692,0.00009423272,0.000107317,0.0001324442,0.00000363174,0.0001789085,0.00005890928,0.00008183583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002326232,"about_ca_system_score_gemma":0.0001278311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004321286,"about_ca_topic_score_gemma":0.000003387068,"domain_scores_codex":[0.9985957,0.00007603338,0.0003245222,0.0003821323,0.0002920768,0.0003295269],"domain_scores_gemma":[0.9988903,0.00001621579,0.0001237303,0.0006576834,0.000184306,0.000127736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005844588,0.00007452683,0.00489635,0.00009315681,0.00002620642,0.000001952445,0.000006381297,0.00005423907,0.9912184,0.0002599234,0.0001271549,0.003183202],"study_design_scores_gemma":[0.0006217374,0.000370047,0.02115395,0.0001754962,0.000007517467,0.000001282458,0.000001922609,0.0001570011,0.9419591,0.00002495494,0.03534409,0.0001828801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517043,0.0004769821,0.02519507,0.0001412911,0.00009181962,0.02187438,0.00004639953,0.00004332415,0.000426414],"genre_scores_gemma":[0.981176,0.00008203258,0.005179979,0.00002439606,0.0001905109,0.01285144,7.609812e-7,0.00004117801,0.0004536898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04925934,"threshold_uncertainty_score":0.5251055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963750717473389,"score_gpt":0.2856021384877231,"score_spread":0.2659646313129892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}