{"id":"W2321986278","doi":"10.1177/1753425912441845","title":"Safety, pharmacokinetics and pharmacodynamics of four-hour intravenous infusions of eritoran in healthy Japanese and Caucasian men","year":2012,"lang":"en","type":"article","venue":"Innate Immunity","topic":"Electrolyte and hormonal disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacodynamics; Pharmacokinetics; Medicine; Pharmacology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004848801,0.0003378761,0.0007197319,0.0001077512,0.0002392822,0.0002079928,0.0001414294,0.0003613116,0.0006114481],"category_scores_gemma":[0.001015692,0.000185081,0.0002451179,0.0001298077,0.0003327749,0.0002188163,0.0001239929,0.0003888093,0.0001699058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001681697,"about_ca_system_score_gemma":0.0001419018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000424286,"about_ca_topic_score_gemma":0.0003894325,"domain_scores_codex":[0.9997461,0.0001276977,0.00001741721,0.00004864665,0.00003211422,0.00002809535],"domain_scores_gemma":[0.9995404,0.0001010387,0.0001621356,0.00003894915,0.00002975441,0.0001275771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3540755,0.008714773,0.2276461,0.0004930081,0.001201229,0.001212109,0.002266561,0.001815788,0.2351302,0.0001779337,0.0007662013,0.1665006],"study_design_scores_gemma":[0.009617709,0.2824574,0.6801645,0.00003029784,0.0008895134,0.001563364,0.0006142133,0.002445094,0.02029406,0.0001180633,0.001739988,0.00006577344],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994695,0.000269848,0.00008462428,0.00001174286,0.000003118694,0.00001392473,0.00002647906,0.000004513043,0.0001163773],"genre_scores_gemma":[0.9992846,0.0001989442,0.0001769607,0.00004130544,0.00001603766,0.00003492893,0.00005607322,0.000002820667,0.000188316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007197319,"threshold_uncertainty_score":0.002564371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01734400553596075,"score_gpt":0.3002082099344394,"score_spread":0.2828642043984786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}