{"id":"W2322093746","doi":"10.1152/ajpendo.00517.2002","title":"Effect of heart failure on the regulation of skeletal muscle protein synthesis, breakdown, and apoptosis","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging; National Institutes of Health","keywords":"Skeletal muscle; Internal medicine; Endocrinology; Muscle hypertrophy; Muscle atrophy; Biology; Heart failure; Atrophy; Myofibril; Soleus muscle; Protein turnover; Apoptosis; Wasting; Myocyte; Chemistry; Medicine; Protein biosynthesis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002590913,0.0003075615,0.0004287431,0.0001863142,0.000137738,0.0002002016,0.0001145801,0.0002105094,0.001037878],"category_scores_gemma":[0.0002097621,0.0001012757,0.000236305,0.00007407666,0.0002863781,0.0002084424,0.0002200925,0.0005257903,0.0001240705],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001300589,"about_ca_system_score_gemma":0.0001505476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003337456,"about_ca_topic_score_gemma":0.0006137792,"domain_scores_codex":[0.9998548,0.00003684544,0.00001442628,0.00002495266,0.00002881309,0.00004010278],"domain_scores_gemma":[0.9997597,0.00005794066,0.00004556171,0.00002349939,0.00002222005,0.00009108037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008618941,0.0004275446,0.006629924,0.0001469759,0.00006465691,0.0002582747,0.00004851245,0.0001338803,0.971144,0.00004786804,0.0001465465,0.01233293],"study_design_scores_gemma":[0.0008346267,0.0363122,0.4154906,0.00008591613,0.000237803,0.0009230875,0.0002916131,0.001585004,0.5412074,0.0002456603,0.00274862,0.00003748375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977987,0.001539857,0.0001140639,0.00005687719,0.00002374943,0.000008979312,0.00005834612,0.000008039699,0.0003913217],"genre_scores_gemma":[0.9974656,0.001215643,0.0002225405,0.0001150524,0.000037554,0.00002573349,0.0001855233,0.000005856143,0.0007264045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001037878,"threshold_uncertainty_score":0.00347203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00353064930752007,"score_gpt":0.2196748360352043,"score_spread":0.2161441867276842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}