{"id":"W2322304557","doi":"10.2174/138920312799277938","title":"Comprehensive Comparative Assessment of In-Silico Predictors of Disordered Regions","year":2012,"lang":"en","type":"article","venue":"Current Protein and Peptide Science","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":198,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"In silico; Intrinsically disordered proteins; Computer science; Computational biology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808367,0.00009692527,0.0001610018,0.00007220004,0.000051276,0.000007926574,0.0001726699,0.0000372112,0.000002338762],"category_scores_gemma":[0.00002971537,0.00008193935,0.00003149678,0.0002211641,0.0007168167,0.00001711616,0.0001452456,0.00008006133,1.683475e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009606574,"about_ca_system_score_gemma":0.0001193226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001431314,"about_ca_topic_score_gemma":0.00001018161,"domain_scores_codex":[0.9991869,0.00003999019,0.0002011396,0.000196296,0.0001727814,0.0002028725],"domain_scores_gemma":[0.9994726,0.000008876033,0.0001287182,0.0002033853,0.0001047305,0.00008174982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002197232,0.00012268,0.2075751,0.00009903783,0.000008378916,7.189571e-8,0.0004258532,0.00003944054,0.7849403,0.005228308,0.0000264551,0.001512469],"study_design_scores_gemma":[0.0007134506,0.0003737299,0.8095818,0.0001624692,0.00001121778,0.000004645082,0.000514869,0.0005086469,0.1829739,0.0006769146,0.004229737,0.0002485762],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956189,0.001908024,0.001412293,0.0000154788,0.0001153766,0.0003956532,0.00001918469,0.00000260272,0.0005124708],"genre_scores_gemma":[0.9985319,0.0001087063,0.001263002,0.000005448185,0.00003424676,0.00002464186,0.0000131998,0.00000297502,0.00001584065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6020068,"threshold_uncertainty_score":0.334139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951236694756512,"score_gpt":0.3371507582559853,"score_spread":0.3076383913084202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}