{"id":"W2322397021","doi":"10.14227/dt180111p39","title":"Dissolution Enhancement and Physicochemical Characterization of Valsartan in Solid Dispersions with β-CD, HP β-CD, and PVP K-30","year":2011,"lang":"en","type":"article","venue":"Dissolution Technologies","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Dissolution; Valsartan; Chemistry; Characterization (materials science); Chromatography; Nuclear chemistry; Pharmacology; Chemical engineering; Materials science; Nanotechnology; Medicine; Organic chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978227,0.0002728303,0.0002397812,0.0001855062,0.00009603535,0.0001806617,0.0001059885,0.0001526169,0.0003292488],"category_scores_gemma":[0.0002561664,0.0001784817,0.0002104717,0.0001511042,0.0002137233,0.0001612239,0.0001358016,0.000410886,0.0001088973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000182915,"about_ca_system_score_gemma":0.000149781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004993803,"about_ca_topic_score_gemma":0.000528026,"domain_scores_codex":[0.9998699,0.00003015928,0.00001596394,0.00002554795,0.00004448186,0.00001390659],"domain_scores_gemma":[0.9998438,0.00004616328,0.00005086147,0.00001064462,0.00002776452,0.00002070734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007881584,0.0000234246,0.0001194208,0.00002676222,0.000004098627,0.00002809518,0.00001643172,0.0001158711,0.9987165,0.00002056648,0.000007736799,0.0008423463],"study_design_scores_gemma":[0.00001204641,0.0003644145,0.001889388,0.000004437523,0.0000142704,0.00009372104,0.0000165156,0.001399043,0.9956195,0.00001970156,0.0005634006,0.000003694806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995611,0.001091785,0.002588282,0.00003886387,0.00001262169,0.00002253603,0.00009182272,0.00002091147,0.0005222828],"genre_scores_gemma":[0.991483,0.001286167,0.005633111,0.00002552224,0.00001122651,0.00004123446,0.0002255313,0.00002103894,0.00127309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004993803,"threshold_uncertainty_score":0.001327097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06533074441701203,"score_gpt":0.3477421298189015,"score_spread":0.2824113854018895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}