{"id":"W2322784754","doi":"10.1097/mib.0000000000000422","title":"Ecobiotherapy Rich in Firmicutes Decreases Susceptibility to Colitis in a Humanized Gnotobiotic Mouse Model","year":2015,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; McMaster University; Population Health Research Institute; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada","keywords":"Firmicutes; Microbiology; Colitis; Gut flora; Biology; Immunology; Feces; Bacteria; 16S ribosomal RNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002946142,0.0007667139,0.0006480094,0.0006984633,0.0002041874,0.0004473525,0.0002579929,0.0006769042,0.002624324],"category_scores_gemma":[0.0001563062,0.0002603162,0.000499475,0.0002656091,0.0004619343,0.0003107337,0.0002998924,0.001413175,0.000478914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002260092,"about_ca_system_score_gemma":0.0002808861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000271529,"about_ca_topic_score_gemma":0.0005684946,"domain_scores_codex":[0.9997546,0.00004221229,0.00001652324,0.00006942011,0.00006234695,0.00005489655],"domain_scores_gemma":[0.9997428,0.00001814515,0.00009020155,0.00002612211,0.00002222435,0.0001004941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002314632,0.001034463,0.0004325052,0.0001215901,0.00002503358,0.00007113411,0.00002150447,0.00008596663,0.9931778,0.00003752571,0.0001114229,0.002566495],"study_design_scores_gemma":[0.0007489264,0.03457425,0.01851532,0.0001275731,0.0002665441,0.0007997081,0.0002231998,0.001609536,0.9348899,0.0002498082,0.007956526,0.00003873242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932881,0.002296224,0.001892027,0.0002800836,0.0001082041,0.0001061635,0.0006546366,0.0001657953,0.001208872],"genre_scores_gemma":[0.9877723,0.002318835,0.003397424,0.0003778841,0.00004158844,0.0002552282,0.001303502,0.00006689149,0.004466389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002624324,"threshold_uncertainty_score":0.008779287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0170967279626378,"score_gpt":0.2765172399992158,"score_spread":0.259420512036578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}