{"id":"W2322937644","doi":"10.1515/hsz-2016-0129","title":"Granzyme B inhibits keratinocyte migration by disrupting epidermal growth factor receptor (EGFR)-mediated signaling","year":2016,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Granzyme; Granzyme B; Wound healing; Epidermal growth factor receptor; Cell biology; Cell migration; Epidermal growth factor; Cancer research; Chemistry; Immunology; Receptor; Medicine; Biology; Cell; Perforin; T cell; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205,0.0002364347,0.0003217311,0.00001416506,0.0001252365,0.00001963645,0.00006798311,0.0003208347,0.0006613186],"category_scores_gemma":[0.0007209627,0.0001277055,0.0001113359,0.00009199105,0.00009786418,0.00005006784,0.00003120263,0.0001669774,0.0001365579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001394099,"about_ca_system_score_gemma":0.00004203206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002899828,"about_ca_topic_score_gemma":6.947291e-7,"domain_scores_codex":[0.9986186,0.0000463685,0.0003640235,0.000424765,0.0001770604,0.0003691742],"domain_scores_gemma":[0.999078,0.0002995323,0.0001240895,0.000150298,0.00009313875,0.0002549002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000124983,0.000138664,0.08160128,0.00004512802,0.00003789443,0.00001333265,0.00003601234,4.273465e-8,0.9161158,0.000003278358,0.0009952205,0.000888423],"study_design_scores_gemma":[0.001720925,0.000172125,0.006425236,0.0001875705,0.00002378718,0.00002510707,0.00002569411,0.000009314979,0.9891601,0.00003478596,0.002003255,0.0002120555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965049,0.0003730219,0.0001351293,0.001992456,0.00005711432,0.0001625266,0.0001663918,0.0002002242,0.000408237],"genre_scores_gemma":[0.9971316,0.0001450833,0.0004269988,0.0002693923,0.0003477819,0.00003181788,0.0006234671,0.00001642426,0.001007435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07517604,"threshold_uncertainty_score":0.7240975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03359580762400567,"score_gpt":0.275261221873299,"score_spread":0.2416654142492933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}