{"id":"W2323011485","doi":"10.1021/jo401122j","title":"Influence of Chlorine Substitution on the Hydrolytic Stability of Biaryl Ether Nucleoside Adducts Produced by Phenolic Toxins","year":2013,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Radical Photochemical Reactions","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge; University of Guelph","funders":"Western Canada Research Grid; Compute Canada","keywords":"Chemistry; Adduct; Hydrolysis; Medicinal chemistry; Protonation; Pyridine; Titration; Substituent; Ether; Chlorine; Polar effect; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005542508,0.0001942162,0.0003281705,0.00001372189,0.00006993624,0.0000121941,0.0007665561,0.0001756436,0.004897769],"category_scores_gemma":[0.002560423,0.0001137115,0.0001236445,0.0002417936,0.0004649296,0.0001305753,0.00007734451,0.0009887536,0.00002162917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001915641,"about_ca_system_score_gemma":0.0001895156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005392504,"about_ca_topic_score_gemma":6.839426e-7,"domain_scores_codex":[0.998276,0.0000383226,0.0007449226,0.0001599656,0.0005532995,0.0002274897],"domain_scores_gemma":[0.9972374,0.0006796069,0.0008272793,0.0007862009,0.0003364034,0.0001330701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007963307,0.0002770339,0.0001605694,0.0001361529,0.00008265362,6.51125e-7,0.0001809925,0.00004934837,0.9984857,0.000009127583,0.0004729077,0.00006519008],"study_design_scores_gemma":[0.0003374112,0.00002585565,0.00032426,0.0001321369,0.00008270711,0.00005242122,0.0001258983,0.00003659166,0.9982294,0.0004143571,0.0001332073,0.0001057496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971451,0.000126552,0.000005203885,0.001342398,0.00002089288,0.0001274134,0.00001467252,0.00001501311,0.00120276],"genre_scores_gemma":[0.9996041,0.00006071277,0.00001299833,0.00006710744,0.0001276539,0.000005448916,0.000002001495,0.00002453801,0.00009544801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00487614,"threshold_uncertainty_score":0.9960119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01126477810618298,"score_gpt":0.2135753117428378,"score_spread":0.2023105336366548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}