{"id":"W2323041537","doi":"10.1097/00007691-200110000-00003","title":"Effect of Cyclosporine on Mycophenolic Acid Area Under the Concentration–Time Curve in Pediatric Kidney Transplant Recipients","year":2001,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Mycophenolic acid; Area under the curve; Mycophenolate; Pharmacokinetics; Ciclosporin; Bioavailability; Calcineurin; Trough level; Pharmacology; Medicine; Urology; Therapeutic drug monitoring; Chemistry; Transplantation; Internal medicine; Tacrolimus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002893835,0.0002223159,0.0003461063,0.0000977193,0.0000656709,0.00001241155,0.0001127463,0.00005517079,0.00005578864],"category_scores_gemma":[0.000008014986,0.0001358884,0.0001125466,0.000344477,0.00003273968,0.00006369573,0.00000541428,0.0001931033,0.00004536375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001062939,"about_ca_system_score_gemma":0.00004545291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005721776,"about_ca_topic_score_gemma":0.000001397377,"domain_scores_codex":[0.9986417,0.0001416257,0.0003432394,0.0002203897,0.0003727543,0.0002802518],"domain_scores_gemma":[0.9991889,0.0003030383,0.0001022376,0.0002564908,0.00003130108,0.0001180533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001264933,0.0002073052,0.9910234,0.0001070356,0.0001505384,0.00006009257,0.0009243076,0.0001734393,0.002884064,0.00003144217,0.00000263367,0.003170763],"study_design_scores_gemma":[0.006225636,0.000589302,0.9406609,0.0007039482,0.0004758288,0.00004194994,0.00004176307,0.0001136685,0.05090089,0.00004955131,0.0000396446,0.0001569333],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967963,0.0005133409,0.00003178031,0.0003519644,0.0004385741,0.0005433179,0.00001201963,0.00003742409,0.001275328],"genre_scores_gemma":[0.9971759,0.001915482,0.0000180857,0.0001087789,0.0002181132,0.00003722975,0.00003402224,0.0000255392,0.0004668846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05036256,"threshold_uncertainty_score":0.5541368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02002970874903629,"score_gpt":0.2966831699222321,"score_spread":0.2766534611731958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}