{"id":"W2323041537","doi":"10.1097/00007691-200110000-00003","title":"Effect of Cyclosporine on Mycophenolic Acid Area Under the Concentration–Time Curve in Pediatric Kidney Transplant Recipients","year":2001,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Mycophenolic acid; Area under the curve; Mycophenolate; Pharmacokinetics; Ciclosporin; Bioavailability; Calcineurin; Trough level; Pharmacology; Medicine; Urology; Therapeutic drug monitoring; Chemistry; Transplantation; Internal medicine; Tacrolimus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005295405,0.000217948,0.0004577023,0.0002937392,0.0001559943,0.0005542582,0.00008802859,0.000240681,0.000502736],"category_scores_gemma":[0.002828889,0.0001033795,0.0003394249,0.0003974799,0.0002371376,0.0002633081,0.0001529485,0.0005787343,0.0001480591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004381461,"about_ca_system_score_gemma":0.000245209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007788931,"about_ca_topic_score_gemma":0.0006391881,"domain_scores_codex":[0.9995099,0.000159555,0.00003574257,0.00006704902,0.0001531343,0.00007456655],"domain_scores_gemma":[0.9977449,0.00105976,0.0006287859,0.00007840266,0.0001404576,0.0003476757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00685295,0.0002353683,0.9281,0.00006655121,0.0002565082,0.001226892,0.0002187101,0.001018915,0.02141758,0.00007593707,0.0002557434,0.04027472],"study_design_scores_gemma":[0.00004968568,0.004587046,0.9818,0.00001159324,0.0001589012,0.002574912,0.00008724683,0.001366073,0.008354013,0.00002974494,0.0009691292,0.00001178242],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983209,0.001057445,0.0001445382,0.00003026901,0.000004978705,0.000003291862,0.00004059834,0.00001005139,0.00038783],"genre_scores_gemma":[0.999499,0.0002313922,0.00009950743,0.00002362143,0.00001016662,0.000002911153,0.00007069956,0.00000474833,0.00005787265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007788931,"threshold_uncertainty_score":0.003178954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02002970874903629,"score_gpt":0.2966831699222321,"score_spread":0.2766534611731958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}