{"id":"W2323138189","doi":"10.1158/0008-5472.sabcs11-p4-16-08","title":"P4-16-08: Pilot Randomized Trial of De-Escalated (q12 Weekly) Versus Standard (q3-4 Weekly) Intravenous Bisphosphonates in Women with Low-Risk Bone Metastases from Breast Cancer.","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Toronto; Princess Margaret Cancer Centre; University of Ottawa","funders":"","keywords":"Medicine; Randomization; N-terminal telopeptide; Breast cancer; Randomized controlled trial; Bone pain; Internal medicine; Surgery; Brief Pain Inventory; Cancer; Physical therapy; Alkaline phosphatase; Chronic pain","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002565592,0.002385469,0.002847821,0.0005870907,0.000493861,0.00111662,0.001661293,0.002533191,0.01270676],"category_scores_gemma":[0.002729471,0.001073562,0.001342495,0.000446701,0.002086972,0.001564064,0.0007808097,0.004079802,0.002149177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008935009,"about_ca_system_score_gemma":0.001627685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009709764,"about_ca_topic_score_gemma":0.00151007,"domain_scores_codex":[0.9990963,0.0005413403,0.00004770029,0.0001333232,0.00004331488,0.0001379459],"domain_scores_gemma":[0.9984811,0.0004285045,0.0002942405,0.0001554858,0.00009031937,0.0005503111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9749922,0.01329818,0.0003588078,0.0002398012,0.0001825608,0.00003424509,0.00004955861,0.0002172409,0.002110529,0.00007329116,0.0004654384,0.007978026],"study_design_scores_gemma":[0.9106891,0.08782458,0.0006933695,0.00001049133,0.00005912688,0.0000191561,0.00001681456,0.000181037,0.0001849881,0.00008190546,0.0002329237,0.000006588105],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875739,0.0009882234,0.0005022162,0.0008465936,0.0004327098,0.006916355,0.0008971596,0.0001477588,0.001694873],"genre_scores_gemma":[0.9743727,0.0008857556,0.002519049,0.001160403,0.0005107975,0.01382601,0.001099138,0.0000326959,0.005593321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01270676,"threshold_uncertainty_score":0.04250836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05347406223543602,"score_gpt":0.3628406865275254,"score_spread":0.3093666242920894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}