{"id":"W2323227628","doi":"10.2174/138161211795049679","title":"Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Apoptosis","year":2011,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-François d'Assise","funders":"Interreg; Institut National de la Santé et de la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Neuroprotection; Pituitary adenylate cyclase-activating peptide; Apoptosis; Programmed cell death; Adenylate kinase; Signal transduction; PI3K/AKT/mTOR pathway; Cell biology; Receptor; Cytochrome c; Protein kinase B; Caspase; Glutamate receptor; Biology; Endocrinology; Pharmacology; Internal medicine; Medicine; Vasoactive intestinal peptide; Neuropeptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003399497,0.000730424,0.001019982,0.001269126,0.0002348602,0.0006633103,0.0007004925,0.0007243003,0.002039606],"category_scores_gemma":[0.0002502834,0.0002318619,0.0002423204,0.00112393,0.000431323,0.000897661,0.0004156889,0.001133489,0.001781976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004783517,"about_ca_system_score_gemma":0.0004667838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006356033,"about_ca_topic_score_gemma":0.001008681,"domain_scores_codex":[0.9999131,0.0000126001,0.00001327142,0.00001656378,0.00003405389,0.00001043868],"domain_scores_gemma":[0.9999146,0.00002744104,0.00001484957,0.000003461679,0.00002563661,0.00001391708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001310644,0.000113423,0.0001520891,0.008762849,0.00005450351,0.0004641508,0.00005250912,0.0004954515,0.0132248,0.003525656,0.01767866,0.955345],"study_design_scores_gemma":[0.00005772396,0.0001931352,0.001595956,0.00114828,0.00007365108,0.002236672,0.00006187357,0.0001618793,0.005035417,0.002417921,0.9869904,0.00002715587],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007493728,0.9962728,0.000279321,0.0002176097,0.0001620601,0.000007772944,0.00002830436,0.00001601948,0.002266772],"genre_scores_gemma":[0.00260188,0.9954671,0.0003821068,0.0001369834,0.0001277262,0.00001371123,0.00004793515,0.000002650594,0.001219876],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002039606,"threshold_uncertainty_score":0.006823182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2626487745858853,"score_gpt":0.4031662886421906,"score_spread":0.1405175140563053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}