{"id":"W2323227628","doi":"10.2174/138161211795049679","title":"Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Apoptosis","year":2011,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-François d'Assise","funders":"Interreg; Institut National de la Santé et de la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Neuroprotection; Pituitary adenylate cyclase-activating peptide; Apoptosis; Programmed cell death; Adenylate kinase; Signal transduction; PI3K/AKT/mTOR pathway; Cell biology; Receptor; Cytochrome c; Protein kinase B; Caspase; Glutamate receptor; Biology; Endocrinology; Pharmacology; Internal medicine; Medicine; Vasoactive intestinal peptide; Neuropeptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002492557,0.0009570873,0.00210886,0.0002965644,0.0001939101,0.00004188292,0.0009422481,0.0002764405,0.00006166774],"category_scores_gemma":[0.001218457,0.0007581911,0.0008225262,0.0007144418,0.0004802421,0.0002481144,0.0004598697,0.001905121,0.0003298997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001119923,"about_ca_system_score_gemma":0.0002178826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002197503,"about_ca_topic_score_gemma":2.559779e-8,"domain_scores_codex":[0.9942111,0.002048102,0.001052078,0.001366292,0.0003708994,0.0009515818],"domain_scores_gemma":[0.9958137,0.002430806,0.0007700348,0.0005105864,0.00006446802,0.0004104536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008093503,0.0003978108,1.921398e-7,0.01913167,0.00005841404,0.00002790069,0.000029449,0.000001891846,0.1214152,0.0005431471,0.0002214569,0.858092],"study_design_scores_gemma":[0.0006401481,0.0007683657,0.000002541443,0.01754224,0.0006963441,0.00002389115,0.000002626512,0.0001175727,0.3122752,0.0004754212,0.6663223,0.001133351],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002426462,0.9917684,0.001301779,0.000004654772,0.001382538,0.004390939,0.00006312037,0.0002160487,0.0006299245],"genre_scores_gemma":[0.004828692,0.9938086,0.0001942526,0.0001366546,0.0003495866,0.0004803811,0.000009877021,0.0001661221,0.00002578924],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8569586,"threshold_uncertainty_score":0.9994869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2626487745858853,"score_gpt":0.4031662886421906,"score_spread":0.1405175140563053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}