{"id":"W2323314923","doi":"10.1038/sj.cgt.7700079","title":"Highly efficient suicide gene expression in hepatocellular carcinoma cells by Epstein-Barr virus-based plasmid vectors combined with polyamidoamine dendrimer","year":2000,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Calgary","keywords":"Transfection; Suicide gene; Thymidine kinase; Plasmid; Herpes simplex virus; Genetic enhancement; Molecular biology; Virology; Ganciclovir; Viral vector; Vector (molecular biology); Gene delivery; Virus; Biology; Hepatitis B virus; Oncolytic virus; Cationic liposome; Cell culture; Cancer research; Gene; Recombinant DNA; Human cytomegalovirus; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002921375,0.0003517812,0.0003249795,0.0002197721,0.0001977752,0.00040052,0.0002174513,0.0003080023,0.0004466416],"category_scores_gemma":[0.0001500786,0.0002020537,0.0002955418,0.0002471961,0.0002340751,0.0003716194,0.0002919532,0.0004737721,0.000279183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003777452,"about_ca_system_score_gemma":0.0002968563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008352534,"about_ca_topic_score_gemma":0.00083243,"domain_scores_codex":[0.9998314,0.00002482589,0.00001569784,0.00003061584,0.00005246048,0.00004487353],"domain_scores_gemma":[0.9999297,0.00001851846,0.00001582319,0.00001258319,0.00001053225,0.00001290838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004034026,0.00000833765,0.0000518596,0.00002050003,0.000003033942,0.00003540696,0.00002676963,0.00006826516,0.9985474,0.0002493238,0.00001848082,0.0009302877],"study_design_scores_gemma":[0.00000623665,0.00004242957,0.0002166323,0.000001462106,0.000007881144,0.00005672649,0.00000596461,0.0005060449,0.998483,0.00002584919,0.0006455641,0.000002268947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808769,0.001202817,0.01567563,0.0001019083,0.00004158564,0.0000450208,0.0001425217,0.0001407346,0.001772893],"genre_scores_gemma":[0.9911135,0.0006280592,0.004828615,0.00001413931,0.000007805789,0.00002915071,0.0001961228,0.00003591875,0.003146851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008352534,"threshold_uncertainty_score":0.002740741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284563257368482,"score_gpt":0.2567765141186727,"score_spread":0.2439308815449879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}