{"id":"W2323314923","doi":"10.1038/sj.cgt.7700079","title":"Highly efficient suicide gene expression in hepatocellular carcinoma cells by Epstein-Barr virus-based plasmid vectors combined with polyamidoamine dendrimer","year":2000,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Calgary","keywords":"Transfection; Suicide gene; Thymidine kinase; Plasmid; Herpes simplex virus; Genetic enhancement; Molecular biology; Virology; Ganciclovir; Viral vector; Vector (molecular biology); Gene delivery; Virus; Biology; Hepatitis B virus; Oncolytic virus; Cationic liposome; Cell culture; Cancer research; Gene; Recombinant DNA; Human cytomegalovirus; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002849275,0.0005701944,0.0004648444,0.0001673738,0.00016178,0.00004680302,0.0005978991,0.0002751914,0.0006662267],"category_scores_gemma":[0.00000399437,0.0004895785,0.0001526866,0.0004268028,0.0002295333,0.000007352714,0.00004434518,0.0002642709,0.00003920528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001758856,"about_ca_system_score_gemma":0.0004656705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005988697,"about_ca_topic_score_gemma":0.0003814198,"domain_scores_codex":[0.9967871,0.0003010956,0.0004435146,0.001009582,0.0005550386,0.0009036534],"domain_scores_gemma":[0.9984295,0.00003801905,0.0001280589,0.0009869676,0.0001167752,0.0003006963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01955804,0.0008168059,0.005241025,0.0000138465,0.00008160638,0.00003882896,0.0001025056,0.007699755,0.9623793,2.598085e-7,0.001141912,0.002926125],"study_design_scores_gemma":[0.01142467,0.004941407,0.0005117361,0.00003812794,0.00001333208,0.000003585856,0.00001537386,0.001623474,0.9754397,0.000001819962,0.005366702,0.0006201067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798937,0.01837553,0.000159497,0.000184443,0.0001417422,0.0009331302,0.0002072142,0.00004348791,0.00006118499],"genre_scores_gemma":[0.994033,0.002646752,0.0002334614,0.001084403,0.0002076553,0.0003634577,0.0004264466,0.0001664437,0.000838389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01572878,"threshold_uncertainty_score":0.9997556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284563257368482,"score_gpt":0.2567765141186727,"score_spread":0.2439308815449879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}