{"id":"W2323406596","doi":"10.1534/g3.115.024257","title":"Chromoanasynthetic Genomic Rearrangement Identified in a <i>N</i>-Ethyl-<i>N</i>-Nitrosourea (ENU) Mutagenesis Screen in <i>Caenorhabditis elegans</i>","year":2015,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Caenorhabditis elegans; Biology; Mutagenesis; Genetics; Point mutation; Phenotype; Ethyl methanesulfonate; Mutagen; Mutation; Mutant; Nitrosourea; Genome; Gene; Molecular biology; Carcinogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007142815,0.0005831647,0.0005550194,0.0005912589,0.00007353667,0.00009639347,0.0007307496,0.0003576453,0.000036221],"category_scores_gemma":[0.00002156941,0.0006770283,0.0001945349,0.0007653,0.0001326702,0.00001111958,0.0004290733,0.00023222,0.00007104754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001353822,"about_ca_system_score_gemma":0.0002445078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003479289,"about_ca_topic_score_gemma":0.002638201,"domain_scores_codex":[0.9964436,0.0001786696,0.0008684417,0.001025644,0.000455916,0.001027758],"domain_scores_gemma":[0.9981906,0.00002339155,0.0001575531,0.001102856,0.0001371588,0.0003883764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403081,0.0001878809,0.02996617,0.00007310379,0.0000929046,0.0001005538,0.0005276981,0.02992268,0.8051102,0.000008497681,0.001420371,0.1324496],"study_design_scores_gemma":[0.005142834,0.000754968,0.02075541,0.0000926084,0.0001282159,0.0001643365,0.001082578,0.001553571,0.511814,0.0002269673,0.4563291,0.001955418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7084284,0.2865402,0.002412128,0.0001347125,0.0004993669,0.0007162777,0.0000942153,0.00004049613,0.001134179],"genre_scores_gemma":[0.9213203,0.07295553,0.003646586,0.0003253678,0.0005740427,0.0001529525,0.000286583,0.0001602293,0.0005784051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4549087,"threshold_uncertainty_score":0.9995681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01483175597839187,"score_gpt":0.2774705820005817,"score_spread":0.2626388260221899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}