{"id":"W2323406596","doi":"10.1534/g3.115.024257","title":"Chromoanasynthetic Genomic Rearrangement Identified in a <i>N</i>-Ethyl-<i>N</i>-Nitrosourea (ENU) Mutagenesis Screen in <i>Caenorhabditis elegans</i>","year":2015,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Caenorhabditis elegans; Biology; Mutagenesis; Genetics; Point mutation; Phenotype; Ethyl methanesulfonate; Mutagen; Mutation; Mutant; Nitrosourea; Genome; Gene; Molecular biology; Carcinogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007749376,0.00036332,0.0002078498,0.0003508693,0.0002479519,0.0001805592,0.0001978121,0.0003732513,0.001409043],"category_scores_gemma":[0.0001145093,0.0001806234,0.0002835779,0.0001743623,0.0002674968,0.00008808904,0.0003206625,0.000390294,0.000267778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000259266,"about_ca_system_score_gemma":0.000274252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00203752,"about_ca_topic_score_gemma":0.006063916,"domain_scores_codex":[0.9998308,0.0000136306,0.00001170687,0.00005772675,0.00006250089,0.00002366301],"domain_scores_gemma":[0.9998612,0.0000244624,0.00005197376,0.00001550615,0.000009680616,0.00003709565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001791362,0.000007712626,0.0003298925,0.00001230318,0.000004755056,0.0001343123,0.000006836417,0.00003377518,0.9987761,0.00002742459,0.00001498656,0.0006339325],"study_design_scores_gemma":[0.000009926264,0.0002265516,0.03381736,0.00001075838,0.0000343958,0.001697277,0.00004995695,0.0005268729,0.961846,0.00003917066,0.001731321,0.00001029054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916077,0.0003261554,0.004792456,0.00005163443,0.00001954144,0.00007228897,0.001018917,0.0001771113,0.001934253],"genre_scores_gemma":[0.9899307,0.000295808,0.006424365,0.00006720491,0.000003401292,0.00003139787,0.001011702,0.00006590141,0.002169413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00203752,"threshold_uncertainty_score":0.004713774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01483175597839187,"score_gpt":0.2774705820005817,"score_spread":0.2626388260221899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}