{"id":"W2323430328","doi":"10.1016/s1873-9946(12)60320-1","title":"P300 Health related quality of life results through week 22 from the CERTIFI study, a multicenter, randomized, double-blind, placebo-controlled Phase2b study of ustekinumab in patients with moderately to severely active Crohn's disease","year":2012,"lang":"en","type":"article","venue":"Journal of Crohn s and Colitis","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of Calgary; Robarts Clinical Trials","funders":"","keywords":"Ustekinumab; Medicine; Placebo; Multicenter study; Double blind; Randomized controlled trial; Health related quality of life; Quality of life (healthcare); Physical therapy; Family medicine; Internal medicine; Alternative medicine; Disease; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001726412,0.001148624,0.002192684,0.0003306031,0.0004662386,0.0007830812,0.0005439039,0.001430407,0.003762917],"category_scores_gemma":[0.001766385,0.0003876025,0.001522528,0.0002669837,0.00048089,0.0007539554,0.00043169,0.002723317,0.0004973562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003637986,"about_ca_system_score_gemma":0.0004794603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006342832,"about_ca_topic_score_gemma":0.001222544,"domain_scores_codex":[0.999446,0.0002305521,0.00004329737,0.00009785176,0.00007802747,0.0001043825],"domain_scores_gemma":[0.9992247,0.0002005007,0.0001734674,0.00006709794,0.0000696131,0.0002647678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9083768,0.01101345,0.005812086,0.0005628574,0.001716397,0.00006840679,0.00008672529,0.0005870975,0.008648622,0.00005565094,0.002167636,0.06090437],"study_design_scores_gemma":[0.5846866,0.2895427,0.115679,0.0000816215,0.003391556,0.0001587193,0.00007302025,0.0009928317,0.00313449,0.0002568262,0.001927243,0.00007534851],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908455,0.004780418,0.0002780726,0.0003907778,0.0001085669,0.0005520865,0.00147879,0.00005893046,0.001506876],"genre_scores_gemma":[0.995023,0.001037156,0.0003997452,0.0003814603,0.0001405279,0.0005594503,0.001475472,0.00001575973,0.0009674652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003762917,"threshold_uncertainty_score":0.01258826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03258187351232168,"score_gpt":0.3045747114427925,"score_spread":0.2719928379304709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}