{"id":"W2323500518","doi":"10.1097/00008390-200008000-00002","title":"Upregulation of interleukin-12 receptor on peripheral blood mononuclear cells and HLA class I, HLA class II or ICAM-1 on melanoma cells by B7.1 and interleukin-12: a mechanism for immunostimulatory impact of melanoma cells adenovirally transfected with B7.1 and IL12?","year":2000,"lang":"en","type":"article","venue":"Melanoma Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Interleukin 12; Peripheral blood mononuclear cell; Melanoma; Cytotoxic T cell; Immunology; Interleukin 21; Antigen-presenting cell; Immune system; Cancer research; Biology; T cell; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009564484,0.0003850067,0.0002855982,0.0001414673,0.0001188145,0.0003712107,0.0001177436,0.0003330859,0.00169423],"category_scores_gemma":[0.000106381,0.0001115639,0.000244089,0.00008051237,0.00014038,0.0001925847,0.0001715745,0.0005624096,0.0005027413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588986,"about_ca_system_score_gemma":0.00009873852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002258645,"about_ca_topic_score_gemma":0.0002651137,"domain_scores_codex":[0.9997757,0.00005449164,0.00001513098,0.00004382976,0.00003292975,0.00007792886],"domain_scores_gemma":[0.9999261,0.00001206376,0.0000137858,0.000009251326,0.00001338776,0.0000253983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000086502,0.00002051848,0.0002952997,0.00002855944,0.000002289865,0.00004812078,0.00001789849,0.00001128636,0.9986818,0.0000275204,0.00001861877,0.0007615339],"study_design_scores_gemma":[0.00004475703,0.0005122305,0.01513341,0.00002089047,0.00003373164,0.0004844754,0.0001304804,0.0008989775,0.9804218,0.00007733535,0.00223435,0.000007466379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958263,0.001477121,0.001202884,0.00008612841,0.00003708539,0.00002580552,0.0001412304,0.00003279998,0.001170564],"genre_scores_gemma":[0.9960756,0.0006240319,0.001307176,0.00007432571,0.00001881955,0.00004847711,0.000261256,0.000007549779,0.001582773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00169423,"threshold_uncertainty_score":0.005667746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604017534939046,"score_gpt":0.28717910184825,"score_spread":0.2711389264988596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}