{"id":"W2323727649","doi":"10.1097/00054725-200912002-00161","title":"Dietary Gangliosides improve intestinal integrity and Epithelial Barrier Function in Caco-2 Cells IBD Model Induced by DSS","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Barrier function; Tight junction; Proinflammatory cytokine; Caco-2; Ceramide; Intestinal epithelium; Ganglioside; Chemistry; Tumor necrosis factor alpha; Intestinal mucosa; Prostaglandin E2; Epithelium; Sialic acid; Cell biology; Biochemistry; Inflammation; Immunology; Biology; Cell; Endocrinology; Internal medicine; Medicine; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349988,0.0004637732,0.0007047917,0.0004425384,0.0001651449,0.0002776715,0.0001962992,0.0004640792,0.001020742],"category_scores_gemma":[0.0001556628,0.0001886763,0.0003757365,0.0002473213,0.0001915297,0.0004074667,0.0003003416,0.001090907,0.0001863851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002366043,"about_ca_system_score_gemma":0.0003395726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001380961,"about_ca_topic_score_gemma":0.002506505,"domain_scores_codex":[0.9998637,0.00002294842,0.000018914,0.00001899128,0.00004049303,0.0000348611],"domain_scores_gemma":[0.9998856,0.000008667587,0.00003193266,0.000009089237,0.00002400391,0.00004075682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002782489,0.0006046762,0.0004977784,0.0003807385,0.00004160778,0.0001160212,0.00006314495,0.00008069695,0.9906756,0.0000569845,0.0001525965,0.004547675],"study_design_scores_gemma":[0.0004563043,0.01538175,0.02311238,0.0001192502,0.0003626955,0.0003843723,0.0003279008,0.001516837,0.9462771,0.0001645615,0.01186704,0.00002995616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937468,0.003737984,0.0006075519,0.0002529348,0.00007378955,0.00005169319,0.0003048341,0.00008638622,0.001138139],"genre_scores_gemma":[0.9874834,0.004345152,0.00275661,0.0003106769,0.00003790133,0.0001034522,0.0007579919,0.00003630084,0.004168627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001380961,"threshold_uncertainty_score":0.00341469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146595482150568,"score_gpt":0.252888429247454,"score_spread":0.2414224744259483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}