{"id":"W2323770735","doi":"10.1515/bc.2011.023","title":"Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site","year":2011,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"University of Calgary","keywords":"Fibrinolysis; Lysine; Chemistry; Mechanism (biology); Apolipoprotein B; Binding site; Biochemistry; Internal medicine; Amino acid; Medicine; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000146728,0.0003462267,0.0001804482,0.0001475771,0.00006430477,0.0001479737,0.0001641637,0.0002462321,0.0006605145],"category_scores_gemma":[0.000131952,0.0000957906,0.0002323975,0.00007479956,0.0001739005,0.0001735332,0.00008735319,0.000343456,0.0002887408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217175,"about_ca_system_score_gemma":0.00009571446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001808857,"about_ca_topic_score_gemma":0.0002706752,"domain_scores_codex":[0.9999046,0.00002156384,0.000008644357,0.00001645093,0.00002783002,0.00002081043],"domain_scores_gemma":[0.9998477,0.0000370138,0.00006983509,0.00001330766,0.00001151858,0.00002062051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001195577,0.00003316731,0.0001860409,0.00003366971,0.000006326888,0.00005384624,0.000004890421,0.0000449577,0.9979814,0.00003938096,0.00001539491,0.001481316],"study_design_scores_gemma":[0.00003745738,0.001272779,0.003910025,0.000004225755,0.0000177828,0.0006143235,0.00001187268,0.0003113082,0.9921714,0.00004134155,0.001601936,0.000005553485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921868,0.003449233,0.003341298,0.00003671,0.00001980883,0.00003737564,0.00008466364,0.00005219339,0.0007920067],"genre_scores_gemma":[0.9923539,0.001313036,0.004925697,0.0000622555,0.00001164284,0.00002490254,0.0002123465,0.000009449471,0.001086793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006605145,"threshold_uncertainty_score":0.002209604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0738661008465681,"score_gpt":0.2493635280965464,"score_spread":0.1754974272499784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}