{"id":"W2323777391","doi":"10.1158/1538-7445.am2011-2386","title":"Abstract 2386: Overexpression of 14-3-3ζ in mouse mammary gland promotes mammary tumor development and progression by enhancing multiple tumor-associated properties","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; McGill University","funders":"","keywords":"Mammary tumor; Cancer research; Carcinogenesis; Angiogenesis; Biology; Mammary gland; DMBA; Genetically modified mouse; Mouse mammary tumor virus; Transgene; Metastasis; Cancer; Breast cancer; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002212248,0.0007710889,0.0003123042,0.0006595106,0.0002713964,0.0003619517,0.0003683973,0.0005813974,0.003265451],"category_scores_gemma":[0.00008558236,0.0003006593,0.0005336555,0.000344893,0.0004023922,0.0003010041,0.000305498,0.001287409,0.001677748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000675015,"about_ca_system_score_gemma":0.000392778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001191757,"about_ca_topic_score_gemma":0.001052786,"domain_scores_codex":[0.9996516,0.00002955426,0.00003459678,0.00006589024,0.0001185544,0.00009991299],"domain_scores_gemma":[0.9997358,0.0000208622,0.00007305856,0.00003415211,0.00002183897,0.0001143019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001044809,0.0000367205,0.00008895405,0.00001178879,0.000002334292,0.0000295567,0.000006307506,0.00002571609,0.9992564,0.0001038187,0.00003102281,0.0003028471],"study_design_scores_gemma":[0.00002603456,0.000252736,0.001533099,0.000006156423,0.000008706889,0.0001227858,0.00001628993,0.0004377675,0.9958106,0.00004876645,0.001734016,0.000003074106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872377,0.001415826,0.004846471,0.0003189824,0.0001015463,0.00009023204,0.002516008,0.0003750357,0.00309831],"genre_scores_gemma":[0.9692031,0.001030255,0.004989591,0.0001095551,0.00003649209,0.0001362037,0.003051068,0.0001475092,0.02129615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003265451,"threshold_uncertainty_score":0.01092398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05022869352322584,"score_gpt":0.3278741668603003,"score_spread":0.2776454733370745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}