{"id":"W2323886088","doi":"10.1021/bi3010279","title":"Nuclear Magnetic Resonance Spectral Assignments of α-1,4-Galactosyltransferase LgtC from <i>Neisseria meningitidis</i>: Substrate Binding and Multiple Conformational States","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Heteronuclear molecule; Substrate analog; Galactosyltransferase; Stereochemistry; Crystallography; Active site; Nuclear magnetic resonance spectroscopy; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001321938,0.0002107695,0.0001113954,0.0001455243,0.0001675577,0.0001284427,0.0003169526,0.0002196918,0.001018588],"category_scores_gemma":[0.0003055289,0.0001046379,0.0001147884,0.0001648473,0.0001768217,0.0001319202,0.0001362769,0.0003815812,0.000108059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002975917,"about_ca_system_score_gemma":0.0001879409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001798885,"about_ca_topic_score_gemma":0.002633582,"domain_scores_codex":[0.9999599,0.000006512731,0.000001552602,0.00000951783,0.00001193779,0.00001058934],"domain_scores_gemma":[0.9998751,0.00002051764,0.00003013439,0.00001503382,0.00003538934,0.00002382965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009690272,0.000009667727,0.0004573547,0.00002484295,0.000004513119,0.00005212883,0.00004053221,0.0001382028,0.9975705,0.00008513309,0.00004102974,0.001479206],"study_design_scores_gemma":[0.00001760664,0.0001980271,0.01324132,0.00001103556,0.00002806592,0.0003565086,0.00008726101,0.004870495,0.9796661,0.0001136291,0.00139656,0.00001354674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949536,0.0002840523,0.003414456,0.00005571748,0.000005535655,0.000007343028,0.000121565,0.00003923566,0.001118515],"genre_scores_gemma":[0.9947842,0.0003254451,0.003432607,0.00003847021,0.000004661732,0.00001403151,0.0004995792,0.00002540368,0.0008756396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001798885,"threshold_uncertainty_score":0.003576815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009173498802026229,"score_gpt":0.1964398802847339,"score_spread":0.1872663814827077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}