{"id":"W2323886088","doi":"10.1021/bi3010279","title":"Nuclear Magnetic Resonance Spectral Assignments of α-1,4-Galactosyltransferase LgtC from <i>Neisseria meningitidis</i>: Substrate Binding and Multiple Conformational States","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Heteronuclear molecule; Substrate analog; Galactosyltransferase; Stereochemistry; Crystallography; Active site; Nuclear magnetic resonance spectroscopy; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001101641,0.0002950268,0.0002950517,0.00002126116,0.0001095148,0.00005598666,0.000200438,0.0002159509,0.002434891],"category_scores_gemma":[0.00006803541,0.0003173336,0.00009862371,0.00008070163,0.0001809439,0.0002144098,0.00005071308,0.0001998648,0.00001472579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006486242,"about_ca_system_score_gemma":0.0000411995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004942891,"about_ca_topic_score_gemma":9.430125e-7,"domain_scores_codex":[0.998543,0.00001187917,0.0004473574,0.000305921,0.0002426264,0.0004492326],"domain_scores_gemma":[0.9990546,0.0001773356,0.0001451995,0.0003191554,0.00004075715,0.0002630008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001193505,0.000105357,0.03630014,0.0002172861,0.0000366786,0.000003450622,0.0004632146,0.000001483872,0.9623388,0.00001082511,0.0001204792,0.0002829056],"study_design_scores_gemma":[0.0007378544,0.000008708946,0.003005508,0.0001368929,0.00005238589,0.00001592818,0.0008897609,0.0002998777,0.9938011,0.00002482786,0.00069172,0.0003354132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927944,0.001684816,0.000003330765,0.00002767432,0.00004921106,0.00004592743,0.0008723475,0.00006279774,0.004459517],"genre_scores_gemma":[0.9985064,0.0001700274,0.0002695867,0.00001506517,0.000179886,0.000007928859,0.0005033086,0.00003518703,0.000312556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03329463,"threshold_uncertainty_score":0.9999279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009173498802026229,"score_gpt":0.1964398802847339,"score_spread":0.1872663814827077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}