{"id":"W2323912502","doi":"10.1021/ol5001999","title":"TMP–Magnesium and TMP–Zinc Bases for the Regioselective Metalation of the Cinnoline Scaffold","year":2014,"lang":"en","type":"article","venue":"Organic Letters","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cinnoline; Chemistry; Regioselectivity; Metalation; Magnesium; Acylation; Halide; Aryl; Zinc; Combinatorial chemistry; Surface modification; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001910017,0.0001294026,0.000141908,0.00001735426,0.0001769061,0.00002649237,0.0002343005,0.00006177348,0.0003247672],"category_scores_gemma":[0.0003793986,0.0000829433,0.00008127864,0.000205784,0.000119214,0.00007087852,0.00006736335,0.00009477293,0.000002035518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003806821,"about_ca_system_score_gemma":0.00002560836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009538665,"about_ca_topic_score_gemma":0.00001019712,"domain_scores_codex":[0.999298,0.00002130425,0.0001878821,0.0002017546,0.000147526,0.0001435035],"domain_scores_gemma":[0.9989165,0.0004538619,0.0001700188,0.0003532933,0.00007857208,0.00002774962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000140169,0.00001885697,0.000965119,0.00009599977,0.00004184274,9.402583e-8,0.00011811,0.000005969231,0.9957546,0.0003037188,0.001858858,0.0008228399],"study_design_scores_gemma":[0.0004942488,0.000008666161,0.002143771,0.00001201795,0.000147442,0.000007947453,0.00007967769,0.0004901458,0.9868094,0.0001323739,0.00955999,0.0001143234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742609,0.0001006058,0.003181247,0.0215587,0.0001018915,0.0001392919,0.00001705251,0.00003853166,0.0006018059],"genre_scores_gemma":[0.9974918,0.0000070269,0.00009641353,0.001322352,0.0002572869,0.0000150424,0.00001172217,0.00002211321,0.0007761986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02323097,"threshold_uncertainty_score":0.3555973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00803843197261751,"score_gpt":0.2022101399996223,"score_spread":0.1941717080270048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}