{"id":"W2323922579","doi":"10.15326/jcopdf.2.1.2014.0140","title":"QVA149 Improves Lung Function, Dyspnea, and Health Status Independent of Previously Prescribed Medications and COPD Severity: A Subgroup Analysis from the SHINE and ILLUMINATE Studies","year":2014,"lang":"en","type":"article","venue":"Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto Western Hospital","funders":"Novartis Pharma","keywords":"Indacaterol; Lama; Bronchodilator; Lung function; Medicine; COPD; Muscarinic antagonist; Bronchodilator Agents; Subgroup analysis; Post-hoc analysis; Antagonist; Physical therapy; Anesthesia; Internal medicine; Lung; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008723554,0.0003547918,0.0009122259,0.0002883143,0.0005914896,0.00008764569,0.0002876055,0.00009058057,0.00008145554],"category_scores_gemma":[0.0007214521,0.0002312157,0.000255074,0.0007007258,0.001604954,0.0006122158,0.0003578257,0.0004945046,8.038157e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001177423,"about_ca_system_score_gemma":0.001006442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004074771,"about_ca_topic_score_gemma":0.0002184976,"domain_scores_codex":[0.9964582,0.0006202449,0.0009538756,0.000537703,0.0009726809,0.0004572523],"domain_scores_gemma":[0.9960999,0.0006399533,0.001239462,0.0006210717,0.0008773045,0.0005222881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001429871,0.0004384561,0.7684262,0.001958341,0.007038421,0.00001643891,0.002303144,0.00008411016,0.0008624459,0.0006444179,0.0003979212,0.2164002],"study_design_scores_gemma":[0.001961304,0.0003111591,0.9777219,0.0004290984,0.004863929,0.00008114855,0.00256255,0.007103475,0.00002917964,0.004058631,0.000689465,0.0001881206],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8883014,0.1046353,0.000772886,0.004572819,0.000337252,0.001130967,0.000194254,0.00001851112,0.0000366166],"genre_scores_gemma":[0.9899266,0.009088584,0.0001352226,0.0001788759,0.0003710726,0.00004257598,0.000134711,0.00003383107,0.00008856171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2162121,"threshold_uncertainty_score":0.9428703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566964259828925,"score_gpt":0.2987446929543977,"score_spread":0.2830750503561085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}