{"id":"W2323922579","doi":"10.15326/jcopdf.2.1.2014.0140","title":"QVA149 Improves Lung Function, Dyspnea, and Health Status Independent of Previously Prescribed Medications and COPD Severity: A Subgroup Analysis from the SHINE and ILLUMINATE Studies","year":2014,"lang":"en","type":"article","venue":"Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto Western Hospital","funders":"Novartis Pharma","keywords":"Indacaterol; Lama; Bronchodilator; Lung function; Medicine; COPD; Muscarinic antagonist; Bronchodilator Agents; Subgroup analysis; Post-hoc analysis; Antagonist; Physical therapy; Anesthesia; Internal medicine; Lung; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004004064,0.001544479,0.003698144,0.0006579242,0.0004348999,0.001124319,0.0008364808,0.0009744231,0.00287043],"category_scores_gemma":[0.003386578,0.0004732307,0.01427563,0.0008236419,0.0005162981,0.0006348535,0.0007904179,0.001062112,0.00031234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004101778,"about_ca_system_score_gemma":0.0006306607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001551334,"about_ca_topic_score_gemma":0.005379034,"domain_scores_codex":[0.99755,0.001006475,0.0004499516,0.0003872745,0.0003040622,0.0003022927],"domain_scores_gemma":[0.9974247,0.001127853,0.0005611731,0.0004642458,0.000203956,0.0002180456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.481851,0.001427054,0.1889577,0.005134829,0.2723079,0.000548034,0.0002813069,0.001091687,0.0133531,0.0001627507,0.002051177,0.03283344],"study_design_scores_gemma":[0.111275,0.03109877,0.6207666,0.0004279018,0.2282092,0.000667781,0.0003606797,0.001043102,0.002141356,0.0004330261,0.00342148,0.0001551553],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981979,0.0130335,0.0005628539,0.0001997474,0.000150064,0.0005447016,0.002485551,0.00002560174,0.001018863],"genre_scores_gemma":[0.9953688,0.001469399,0.000316367,0.0002392198,0.0002064264,0.0002806427,0.001732418,0.0000133898,0.0003732477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004004064,"threshold_uncertainty_score":0.02117574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566964259828925,"score_gpt":0.2987446929543977,"score_spread":0.2830750503561085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}