{"id":"W2323977027","doi":"10.1021/jf102120c","title":"Egg-Derived Peptide IRW Inhibits TNF-α-Induced Inflammatory Response and Oxidative Stress in Endothelial Cells","year":2010,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"University of Alberta","keywords":"Superoxide; Tumor necrosis factor alpha; Oxidative stress; Cell adhesion molecule; Monocyte; Chemistry; Inflammation; VCAM-1; Endothelial stem cell; Superoxide dismutase; Angiotensin II; Reactive oxygen species; Biochemistry; Biology; Intracellular; Cell biology; Immunology; ICAM-1; Enzyme; In vitro; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001419558,0.0003887272,0.0003174168,0.0001725222,0.00008706436,0.0001906746,0.0001489389,0.0002208035,0.0007991925],"category_scores_gemma":[0.0001591459,0.00008599261,0.0001851087,0.0001049319,0.0001655058,0.0001743185,0.0001283754,0.0006002411,0.000247976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007148537,"about_ca_system_score_gemma":0.00011748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001327748,"about_ca_topic_score_gemma":0.0001749985,"domain_scores_codex":[0.9999347,0.0000187956,0.000007515432,0.000007888854,0.00001324442,0.00001786155],"domain_scores_gemma":[0.9999223,0.00001454345,0.000023447,0.000008995265,0.00001046077,0.00002018903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004247998,0.0002192941,0.00009207062,0.00006807488,0.000006459669,0.00004965923,0.000008783206,0.00005475022,0.996255,0.00002515647,0.00002767268,0.002768237],"study_design_scores_gemma":[0.0001870915,0.004656726,0.004103856,0.00001520886,0.00002764959,0.0002928931,0.00002694975,0.0006675008,0.9884264,0.00004640859,0.001544682,0.000004558179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957156,0.002004279,0.001297087,0.00005246666,0.00002677791,0.00002760612,0.0000661173,0.00003711707,0.0007727869],"genre_scores_gemma":[0.9949708,0.001474595,0.001812244,0.00005923058,0.00002408414,0.00003400489,0.0003053627,0.00001257549,0.001307123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007991925,"threshold_uncertainty_score":0.002673507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00582433244499769,"score_gpt":0.2036362259575328,"score_spread":0.1978118935125351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}