{"id":"W2323977027","doi":"10.1021/jf102120c","title":"Egg-Derived Peptide IRW Inhibits TNF-α-Induced Inflammatory Response and Oxidative Stress in Endothelial Cells","year":2010,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"University of Alberta","keywords":"Superoxide; Tumor necrosis factor alpha; Oxidative stress; Cell adhesion molecule; Monocyte; Chemistry; Inflammation; VCAM-1; Endothelial stem cell; Superoxide dismutase; Angiotensin II; Reactive oxygen species; Biochemistry; Biology; Intracellular; Cell biology; Immunology; ICAM-1; Enzyme; In vitro; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000240044,0.0001987743,0.0002341996,0.00002759537,0.00006052916,0.00004826116,0.000132522,0.0002191262,0.000008882357],"category_scores_gemma":[0.0001117862,0.0001273785,0.00009232981,0.00005909055,0.0001026615,0.00002184643,0.0001066747,0.0003870565,4.529166e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001214078,"about_ca_system_score_gemma":0.0000481903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004057983,"about_ca_topic_score_gemma":0.00002842305,"domain_scores_codex":[0.9990505,0.00005188267,0.0003385544,0.0002215683,0.0001481428,0.0001893363],"domain_scores_gemma":[0.999269,0.00003190766,0.0003013317,0.0001005251,0.0001478376,0.0001493805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004007223,0.00006585124,0.001920073,0.00003048569,0.0000690396,0.000006671324,0.0001222956,0.000002685596,0.9969288,0.000001069598,0.00004303181,0.0004093286],"study_design_scores_gemma":[0.0008773267,0.0003860021,0.06217259,0.00005238388,0.00001694959,0.0001753559,0.0005292425,7.648044e-7,0.9352714,0.0000131788,0.0003179602,0.000186774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992157,0.000308325,0.000001262178,0.0001681743,0.00005805915,0.00008512793,0.00003677967,0.00000319478,0.0001233936],"genre_scores_gemma":[0.9990855,0.0001635367,0.0001544418,0.00002615462,0.000403661,0.000004696436,0.000009100889,0.00000774846,0.0001451044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06165728,"threshold_uncertainty_score":0.5194344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00582433244499769,"score_gpt":0.2036362259575328,"score_spread":0.1978118935125351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}