{"id":"W2324013304","doi":"10.1021/ja200009c","title":"Palladium-Catalyzed Mono-α-arylation of Acetone with Aryl Halides and Tosylates","year":2011,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Dalhousie University","keywords":"Chemistry; Acetone; Aryl; Reagent; Palladium; Catalysis; Halide; Reactivity (psychology); Selectivity; Solvent; Organic chemistry; Base (topology); Combinatorial chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002498768,0.0008335833,0.0003319966,0.0002730463,0.0002685781,0.0001618895,0.0005949708,0.0002368016,0.001341178],"category_scores_gemma":[0.0002747484,0.0001978474,0.0002851629,0.0003146302,0.0002423992,0.0003193208,0.0005066171,0.0005402564,0.0008449164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002642477,"about_ca_system_score_gemma":0.0003286899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000847122,"about_ca_topic_score_gemma":0.002128115,"domain_scores_codex":[0.9997351,0.00004689955,0.00002416089,0.00004813865,0.00005271419,0.000093036],"domain_scores_gemma":[0.999933,0.00001058235,0.00002037614,0.00001153887,0.00001169862,0.00001281714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001948016,0.00003649416,0.0002237106,0.0003769729,0.00002788267,0.000406261,0.0001126257,0.0005119742,0.9872878,0.001050062,0.0005573381,0.009214142],"study_design_scores_gemma":[0.00001018285,0.00008744232,0.000208427,0.00000515846,0.000009510317,0.0001841594,0.00001246259,0.0001720846,0.9952999,0.00006098458,0.00394394,0.000005701292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.905284,0.009344345,0.05058983,0.0005496562,0.0003432175,0.0002296441,0.00120175,0.000674023,0.03178359],"genre_scores_gemma":[0.9828321,0.004409704,0.007194908,0.00009731582,0.00004067155,0.00004314206,0.0002921735,0.00005071731,0.005039263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001341178,"threshold_uncertainty_score":0.00448662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02083531601388592,"score_gpt":0.2554304054073088,"score_spread":0.2345950893934229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}