{"id":"W2324043781","doi":"10.1038/nrrheum.2016.24","title":"Mitochondria drive NETosis and inflammation in SLE","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Rheumatology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Mitochondrion; Inflammation; Neutrophil extracellular traps; Medicine; Cell biology; Extracellular; Oxidative phosphorylation; Immunology; Respiration; Cellular respiration; Cytokine; Cell; Biology; Biochemistry; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005905158,0.0008304708,0.004645196,0.0006172672,0.0001165349,0.0000199053,0.0005062376,0.003310481,0.0005120827],"category_scores_gemma":[0.0003943186,0.0005232908,0.0004718317,0.0004193436,0.0002306659,0.0001480986,0.0002511209,0.002067974,0.002728808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001254128,"about_ca_system_score_gemma":0.0001505349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001290844,"about_ca_topic_score_gemma":0.00004588159,"domain_scores_codex":[0.9947953,0.001946005,0.001593488,0.0009782163,0.00004718374,0.0006398661],"domain_scores_gemma":[0.9975681,0.0006313423,0.001006778,0.0006754699,0.00006773754,0.00005058066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001254153,0.00002349999,0.00001175662,0.00691546,0.0001746554,0.00001579559,0.00004242642,3.560054e-9,0.0004725904,0.007218153,0.004056726,0.9810564],"study_design_scores_gemma":[0.0006150937,0.0000615834,0.000003065135,0.02620968,0.0002284023,0.000742255,0.000005458466,5.377462e-8,0.0002596535,0.0003346712,0.9710265,0.0005136176],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005805925,0.9951217,0.0000638651,0.0001743886,0.002164443,0.002066546,0.00005648809,0.0000563618,0.0002381808],"genre_scores_gemma":[0.00002584858,0.9978376,0.0001354204,0.0000827822,0.00004944939,0.0005493053,0.0003455789,0.00006642245,0.0009075734],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9805428,"threshold_uncertainty_score":0.9997219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01800730847875659,"score_gpt":0.3047702787837747,"score_spread":0.2867629703050181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}