{"id":"W2324075776","doi":"10.1097/qco.0b013e328359f04a","title":"Are new anthelmintics needed to eliminate human helminthiases?","year":2012,"lang":"en","type":"review","venue":"Current Opinion in Infectious Diseases","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Praziquantel; Anthelmintic; Schistosomiasis; Mass drug administration; Albendazole; Trichuris trichiura; Drug resistance; Regimen; Pharmacology; Intensive care medicine; Immunology; Environmental health; Veterinary medicine; Surgery; Biology; Helminths; Ascaris lumbricoides; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009356379,0.0006529107,0.001479659,0.0008624106,0.0002801763,0.00007319607,0.0003698631,0.0004159401,0.001602681],"category_scores_gemma":[0.0002603724,0.0005948478,0.0006537162,0.000525029,0.00009938922,0.0001529648,0.0002329225,0.0008274609,0.00512473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002824261,"about_ca_system_score_gemma":0.0001911454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002015551,"about_ca_topic_score_gemma":0.00003253239,"domain_scores_codex":[0.9974887,0.0003301028,0.0008388864,0.0005847207,0.00006663271,0.0006910056],"domain_scores_gemma":[0.998104,0.0003148931,0.0007145624,0.0005666175,0.00008459105,0.0002152764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002135429,0.001687929,0.003187498,0.009410096,0.0003583367,0.000002486063,0.0001751053,0.000003255792,0.000006655714,0.0007641162,0.1181316,0.8662515],"study_design_scores_gemma":[0.0004068842,0.00009376415,0.001085509,0.01501089,0.0006718413,0.00007611902,0.00006023144,1.021172e-7,0.000003374442,0.00006027382,0.9819143,0.0006167413],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001642918,0.9760447,0.00004653899,0.00003472175,0.02161339,0.0009724222,0.0006730864,0.000188587,0.0002622693],"genre_scores_gemma":[0.0008229302,0.9953797,0.000002446299,0.00004666201,0.001050221,0.0003352121,0.001600232,0.00007553368,0.0006870033],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8656348,"threshold_uncertainty_score":0.9996503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1367161818246629,"score_gpt":0.4390575913938655,"score_spread":0.3023414095692025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}