{"id":"W2324079694","doi":"10.1021/jf504811x","title":"Kinetic Interactions between Cyclolinopeptides and Immobilized Human Serum Albumin by Surface Plasmon Resonance","year":2015,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome Prairie; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Human serum albumin; Chemistry; Surface plasmon resonance; CLs upper limits; Methionine; Plasma protein binding; Binding site; Serum albumin; Albumin; Biophysics; Biochemistry; Nanoparticle; Nanotechnology; Amino acid; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009369116,0.0001418425,0.0002268862,0.000009269521,0.00009533342,0.00005043649,0.00009668138,0.00007981325,0.000006991332],"category_scores_gemma":[0.00004501132,0.00009265364,0.00008657991,0.00006075223,0.00007400027,0.00001884785,0.00008649684,0.0001720637,6.156254e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001755,"about_ca_system_score_gemma":0.00001219295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001523247,"about_ca_topic_score_gemma":0.000006515651,"domain_scores_codex":[0.9992447,0.00001961475,0.0003070017,0.0001675232,0.0001270079,0.0001341399],"domain_scores_gemma":[0.9993007,0.00001413909,0.0002411942,0.00007832563,0.0002117918,0.0001539011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000337595,0.00003105911,0.007925971,0.00001652214,0.0001570502,8.711542e-7,0.00005334522,0.000008715268,0.9823304,7.163617e-7,0.009108238,0.0003333454],"study_design_scores_gemma":[0.0009277964,0.0005059538,0.02717423,0.00007808317,0.0001160414,0.0002122815,0.001785584,0.000002777815,0.9459736,0.00002169487,0.02297484,0.0002270512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939728,0.005255698,0.00001033019,0.0003820876,0.0000383345,0.00003863503,0.00002783093,0.000003357997,0.0002708711],"genre_scores_gemma":[0.9978673,0.0006171644,0.0001190434,0.00002596039,0.0002773162,0.000001909763,0.00002584321,0.0000053513,0.001060058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03635675,"threshold_uncertainty_score":0.3778306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364053532641178,"score_gpt":0.2497247065791278,"score_spread":0.2360841712527161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}