{"id":"W2324079694","doi":"10.1021/jf504811x","title":"Kinetic Interactions between Cyclolinopeptides and Immobilized Human Serum Albumin by Surface Plasmon Resonance","year":2015,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome Prairie; University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Human serum albumin; Chemistry; Surface plasmon resonance; CLs upper limits; Methionine; Plasma protein binding; Binding site; Serum albumin; Albumin; Biophysics; Biochemistry; Nanoparticle; Nanotechnology; Amino acid; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004508153,0.0004944479,0.0003790828,0.0002082215,0.000199118,0.0003662404,0.0006421378,0.0003904534,0.001050534],"category_scores_gemma":[0.0005778273,0.0003325799,0.0003642314,0.0001864454,0.0002573549,0.0004329442,0.0002490841,0.0007524269,0.0006144277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00056536,"about_ca_system_score_gemma":0.0001495401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267165,"about_ca_topic_score_gemma":0.001457951,"domain_scores_codex":[0.9995397,0.00009432535,0.00002071826,0.0001121383,0.0001226493,0.0001104917],"domain_scores_gemma":[0.9997141,0.0001402951,0.00004802172,0.00001912549,0.00005644813,0.00002199547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001341977,0.00003605152,0.0001956235,0.00005638715,0.00001318815,0.00002999524,0.0000435535,0.0005076615,0.9970543,0.0001007426,0.0001083266,0.001719942],"study_design_scores_gemma":[0.00001495548,0.0002347234,0.00108642,0.000005366835,0.0000105075,0.00003860091,0.00003406035,0.01857439,0.9789416,0.00006639305,0.0009784228,0.0000145443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.971982,0.001416444,0.02273793,0.0002114852,0.00005754552,0.0001004143,0.0002211751,0.0002964845,0.002976485],"genre_scores_gemma":[0.9865388,0.0006435825,0.008700741,0.0001066626,0.00002064266,0.00008071822,0.0003041492,0.00004795842,0.003556701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267165,"threshold_uncertainty_score":0.004102051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364053532641178,"score_gpt":0.2497247065791278,"score_spread":0.2360841712527161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}