{"id":"W2324272684","doi":"10.1021/ct1006967","title":"Distinct Morphologies for Amyloid Beta Protein Monomer: Aβ<sub>1–40</sub>, Aβ<sub>1–42</sub>, and Aβ<sub>1–40</sub>(D23N)","year":2011,"lang":"en","type":"article","venue":"Journal of Chemical Theory and Computation","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Centre National de la Recherche Scientifique; Institut Universitaire de France; Canada Research Chairs","keywords":"BETA (programming language); Monomer; Amyloid (mycology); Amyloid beta; Chemistry; Nanotechnology; Crystallography; Materials science; Physics; Computer science; Polymer; Biochemistry; Peptide; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004851093,0.0001766393,0.0001031112,0.0001859954,0.00022568,0.0002073579,0.0001746888,0.0002501569,0.001273666],"category_scores_gemma":[0.0001634156,0.0001491439,0.0001697442,0.000112317,0.0002434607,0.0001649934,0.0001189892,0.0002750163,0.0002118924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001999259,"about_ca_system_score_gemma":0.0001167974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001076071,"about_ca_topic_score_gemma":0.001177839,"domain_scores_codex":[0.9999675,0.000002184402,0.000001972145,0.00001067234,0.00001250113,0.000005185553],"domain_scores_gemma":[0.9999305,0.00001259825,0.00001935845,0.000007156229,0.00001285638,0.00001756244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0001196064,0.00007292656,0.006767542,0.0000910029,0.00003707928,0.0003169429,0.0001824877,0.01586042,0.9689972,0.001696647,0.0004069581,0.005451321],"study_design_scores_gemma":[0.00008610199,0.00035953,0.1113446,0.00004485135,0.00006476414,0.002184782,0.0004387331,0.2266733,0.6473155,0.004161487,0.007236206,0.00009010737],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933034,0.0003528709,0.004533351,0.00004523097,0.00001070242,0.00001184733,0.0001639279,0.00009938471,0.001479411],"genre_scores_gemma":[0.9941013,0.0002235335,0.00461625,0.00002336329,0.000001567651,0.00001699477,0.0002826035,0.00003653026,0.0006978508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001273666,"threshold_uncertainty_score":0.004260838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0335104770574873,"score_gpt":0.2919420466032395,"score_spread":0.2584315695457522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}