{"id":"W2324421180","doi":"10.1371/journal.pone.0152107","title":"Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association; Heart and Stroke Foundation of Canada","keywords":"Single-nucleotide polymorphism; TCF7L2; CDKN2A; Medicine; Allele; Genotype; Internal medicine; Endocrinology; Biology; Genetics; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008129447,0.0005864431,0.0003111324,0.0004736048,0.0003731375,0.0004180936,0.0003117004,0.0003512097,0.002392235],"category_scores_gemma":[0.001784294,0.0002545223,0.0004905917,0.0005063554,0.0003009651,0.0001979681,0.0002295354,0.0004223633,0.0002160759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001891227,"about_ca_system_score_gemma":0.0001796574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004299584,"about_ca_topic_score_gemma":0.003332398,"domain_scores_codex":[0.9995516,0.0001332934,0.00003541958,0.0001511378,0.00007672192,0.00005188305],"domain_scores_gemma":[0.998664,0.0004814629,0.0004232379,0.0001414879,0.00008802157,0.0002018276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001265908,0.00007266633,0.9894797,0.00002026136,0.0003287127,0.000667714,0.0002134416,0.0001151829,0.003649176,0.00004703509,0.0001834623,0.003956757],"study_design_scores_gemma":[0.00004532901,0.0002881729,0.995955,0.00001130591,0.0002157121,0.00171983,0.0001322394,0.0001894021,0.0009647589,0.00005193806,0.0004188328,0.000007392578],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990765,0.0002359669,0.0002592836,0.00001961924,0.000004006058,0.000002963108,0.0002732046,0.000005697798,0.0001226176],"genre_scores_gemma":[0.9989773,0.0001518983,0.000310465,0.00001499547,0.000006423274,0.00000491193,0.0002326722,0.00000398907,0.0002973611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004299584,"threshold_uncertainty_score":0.008549094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03230099060558575,"score_gpt":0.2177389867760812,"score_spread":0.1854379961704954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}