{"id":"W2324431387","doi":"10.1158/0008-5472.sabcs-09-908","title":"Protective Effect of Estrogen (E2) and Increased Risk of E2 Plus Progestin (Prog) on Breast Cancer (BrCa). The 2009 Review of the Women's Health Initiative (WHI) Hormone Replacement Therapy (HRT) Published Trials.","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; McGill University","funders":"","keywords":"Medicine; Hormone replacement therapy (female-to-male); Breast cancer; Hazard ratio; Hormone therapy; Women's Health Initiative; Gynecology; Estrogen; Progestin; Randomized controlled trial; Internal medicine; Placebo; Cancer; Oncology; Observational study; Pathology; Alternative medicine; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004673699,0.0007581103,0.003263963,0.001641277,0.0001698219,0.001118697,0.0005882476,0.0009228601,0.003919587],"category_scores_gemma":[0.01177825,0.0004599688,0.003446125,0.001538403,0.0003097281,0.0006065701,0.0003788446,0.0007487768,0.0003205038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009568708,"about_ca_system_score_gemma":0.001912426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001857704,"about_ca_topic_score_gemma":0.006344754,"domain_scores_codex":[0.9973314,0.001425106,0.000582933,0.0002292092,0.0003782976,0.00005306549],"domain_scores_gemma":[0.9936996,0.004675941,0.001159372,0.00007013037,0.0003360545,0.00005895103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.008278074,0.00007872032,0.002672119,0.590324,0.03492819,0.0001745534,0.0000946738,0.0003605541,0.001079146,0.000914581,0.01249322,0.3486022],"study_design_scores_gemma":[0.01590383,0.007584036,0.03528501,0.4330326,0.3177197,0.001967994,0.0002971331,0.0003795636,0.002486701,0.003110826,0.1820852,0.0001474934],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009762553,0.997871,0.00004678033,0.0003468742,0.0001495698,0.00006195378,0.0001881465,0.000003170002,0.0003561316],"genre_scores_gemma":[0.01749638,0.9801314,0.0003512399,0.001178012,0.0002229476,0.000117449,0.0001977295,0.000003605355,0.0003011922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004673699,"threshold_uncertainty_score":0.02471721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03040918916464424,"score_gpt":0.3780123453672894,"score_spread":0.3476031562026452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}