{"id":"W2324457823","doi":"10.1136/annrheumdis-2012-eular.2636","title":"FRI0179 Comparison of tocilizumab as monotherapy or in combination with non-biological disease-modifying anti-rheumatic drugs (DMARDs) in patients with rheumatoid arthritis (RA) and an inadequate response to anti-TNF agents","year":2012,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Medicine; Tocilizumab; Leflunomide; Internal medicine; Combination therapy; Rheumatoid arthritis; TNF inhibitor; Methotrexate; Rheumatology; Adalimumab; Hydroxychloroquine; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001246884,0.001055434,0.004155674,0.0007054184,0.0002707932,0.001223637,0.001021495,0.001538612,0.007050507],"category_scores_gemma":[0.001718822,0.0006544088,0.002890402,0.0005303093,0.0006291731,0.001221441,0.0004171469,0.003083694,0.0012635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009000204,"about_ca_system_score_gemma":0.001088517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00166885,"about_ca_topic_score_gemma":0.004140058,"domain_scores_codex":[0.9993656,0.0002545732,0.00007833479,0.0001036023,0.00005883236,0.0001389529],"domain_scores_gemma":[0.999119,0.0003226509,0.0001349951,0.00003909912,0.00003907523,0.000345238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9685439,0.001761503,0.0004727001,0.0005620208,0.001663814,0.00007091689,0.00003437358,0.0002704354,0.00447116,0.0001240065,0.0005939192,0.02143124],"study_design_scores_gemma":[0.687113,0.2912955,0.01023935,0.0001959829,0.004184813,0.0003865694,0.0001334853,0.001795916,0.001965405,0.0002376679,0.002374681,0.00007769942],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731331,0.01949229,0.0004081981,0.0009679336,0.001244841,0.0002449098,0.001305163,0.0001263432,0.003077111],"genre_scores_gemma":[0.9890232,0.005258501,0.0006637144,0.0005355288,0.0006563358,0.0002109785,0.001364754,0.00002605101,0.002260879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007050507,"threshold_uncertainty_score":0.02358633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04304142709805488,"score_gpt":0.3455407365479506,"score_spread":0.3024993094498957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}