{"id":"W2324535812","doi":"10.1158/1538-7445.am2012-2706","title":"Abstract 2706: Phase 2 study with pharmacokinetics (PK) analysis of sorafenib and vinorelbine in metastatic breast cancer","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Vinorelbine; Capecitabine; Sorafenib; Internal medicine; Pharmacokinetics; Metastatic breast cancer; Oncology; Cancer; Breast cancer; Docetaxel; Chemotherapy; Concomitant; Pharmacology; Gastroenterology; Colorectal cancer; Hepatocellular carcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001125317,0.001310701,0.001857458,0.0004301987,0.0003786439,0.0007162116,0.0006290547,0.0006986114,0.003652091],"category_scores_gemma":[0.0009218178,0.0005396609,0.000911227,0.0004021644,0.0007058874,0.0005519657,0.0003424788,0.00187812,0.0008913866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009103878,"about_ca_system_score_gemma":0.001821355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000955212,"about_ca_topic_score_gemma":0.0009729972,"domain_scores_codex":[0.9994481,0.0002582993,0.00002454249,0.00009250084,0.00007048464,0.0001059819],"domain_scores_gemma":[0.9994561,0.00008172334,0.00007250451,0.00005327702,0.00003875948,0.0002975745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6282262,0.1618889,0.01698121,0.0005612795,0.0008254345,0.0008696925,0.000355365,0.004828163,0.09997763,0.0003560976,0.003299204,0.0818309],"study_design_scores_gemma":[0.244644,0.7191728,0.01852247,0.00001714864,0.0002710018,0.0009619718,0.00006804965,0.00221497,0.01072372,0.0001806735,0.003187035,0.00003619174],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967262,0.0004654096,0.0003680994,0.00009576994,0.0000317434,0.001076935,0.0005621462,0.00004448724,0.0006292363],"genre_scores_gemma":[0.9912334,0.000601228,0.001594438,0.000223967,0.0001265422,0.001895966,0.002107629,0.00002730379,0.00218946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003652091,"threshold_uncertainty_score":0.01221746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1254380671873317,"score_gpt":0.5228773848304897,"score_spread":0.397439317643158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}