{"id":"W2324674339","doi":"10.1093/ndt/gfv202.62","title":"SP836PROSPECTIVE, 6 MONTH, OPEN LABEL, CONVERSION STUDY FROM MYCOPHENOLATE MOFETIL TO MYCOPHENOLIC ACID EVALUATING THE SEVERITY OF GASTRO-INTESTINAL SYMPTOMS AND MYCOPHENOLIC ACID URINARY METABOLITE AS A SURROGATE MARKER OF PLASMATIC AREA UNDER THE CURVE","year":2015,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Anorectal Disease Treatments and Outcomes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Mycophenolate; Mycophenolic acid; Medicine; Surrogate endpoint; Metabolite; Urinary system; Gastroenterology; Internal medicine; Urology; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001438481,0.001041648,0.002150216,0.0004164494,0.0006990167,0.0009618872,0.0005016405,0.001423759,0.003182882],"category_scores_gemma":[0.001494777,0.0004450841,0.001245863,0.0004604638,0.001211439,0.001145081,0.0003590908,0.003256127,0.001052937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000638584,"about_ca_system_score_gemma":0.000697123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006266425,"about_ca_topic_score_gemma":0.000789308,"domain_scores_codex":[0.9992616,0.0001917703,0.00005731482,0.0002287522,0.0001476007,0.0001130524],"domain_scores_gemma":[0.9987308,0.0002358191,0.000230474,0.000208931,0.0001438291,0.0004500599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7872429,0.09393138,0.03388087,0.0004211812,0.001259711,0.001003903,0.0003675872,0.0009251004,0.03159905,0.00013025,0.002000185,0.04723785],"study_design_scores_gemma":[0.09093641,0.8158231,0.08251927,0.00003270253,0.0005272648,0.0008710751,0.0001146789,0.001085182,0.004892616,0.0001377858,0.003002457,0.0000574462],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957256,0.0005490801,0.0004077999,0.000101071,0.0001132022,0.000996104,0.0009000504,0.00006036616,0.001146596],"genre_scores_gemma":[0.9942896,0.0003051193,0.0005789424,0.0004477771,0.0001199429,0.0006833824,0.001755363,0.00001778421,0.001802048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003182882,"threshold_uncertainty_score":0.01064783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04273051593656636,"score_gpt":0.326819835189553,"score_spread":0.2840893192529866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}