{"id":"W2324692647","doi":"10.1158/1535-7163.targ-11-b12","title":"Abstract B12: The effects of Irinophore C™ on the microenvironment and vasculature of a primary orthotopic model of colorectal cancer.","year":2011,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Colorectal cancer; Irinotecan; Medicine; Cancer; Tumor microenvironment; Primary tumor; Pathology; In vivo; Cancer research; Internal medicine; Metastasis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002382371,0.0006086012,0.0004271417,0.0003800399,0.0002388758,0.000287574,0.0002898542,0.000355398,0.002980202],"category_scores_gemma":[0.00008744311,0.00023565,0.0004062262,0.000289891,0.0002571685,0.0002619717,0.0001253244,0.00123125,0.0006738545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004000739,"about_ca_system_score_gemma":0.000462395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002183364,"about_ca_topic_score_gemma":0.002872297,"domain_scores_codex":[0.999779,0.00003297971,0.00001332564,0.00005689971,0.00005019606,0.00006760521],"domain_scores_gemma":[0.9997477,0.00003363804,0.00004688154,0.00003207677,0.00002616265,0.0001135785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009589458,0.0004346,0.0001125967,0.00009219624,0.000008171714,0.0000908384,0.00002378886,0.00008868498,0.9962292,0.00006008159,0.0003337234,0.001567152],"study_design_scores_gemma":[0.0001235291,0.007352508,0.00633675,0.0000117441,0.00003192122,0.0004433056,0.00004836275,0.0007582769,0.9812441,0.00002547296,0.003613448,0.0000105379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885142,0.00215084,0.002529413,0.0002512716,0.000174643,0.0001579668,0.001878791,0.0003092442,0.004033659],"genre_scores_gemma":[0.9825021,0.00158244,0.004350367,0.0001445613,0.00004158882,0.0002291512,0.002835778,0.0000558609,0.008258175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002980202,"threshold_uncertainty_score":0.009969771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01955027477734175,"score_gpt":0.2508242462791802,"score_spread":0.2312739715018385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}