{"id":"W2324692647","doi":"10.1158/1535-7163.targ-11-b12","title":"Abstract B12: The effects of Irinophore C™ on the microenvironment and vasculature of a primary orthotopic model of colorectal cancer.","year":2011,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Colorectal cancer; Irinotecan; Medicine; Cancer; Tumor microenvironment; Primary tumor; Pathology; In vivo; Cancer research; Internal medicine; Metastasis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007028254,0.000144993,0.0001786057,0.00001902969,0.00003788974,0.00000355535,0.000200464,0.00008530455,0.00001296663],"category_scores_gemma":[0.0000047304,0.00008655217,0.0001213001,0.00004770653,0.0002832442,0.000002019487,0.00008263998,0.0001070288,1.705329e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003003533,"about_ca_system_score_gemma":0.0001131701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003624021,"about_ca_topic_score_gemma":0.0001068982,"domain_scores_codex":[0.9992247,0.00004826825,0.0001599089,0.0001929,0.0002064747,0.0001677897],"domain_scores_gemma":[0.9994329,0.00002126426,0.0001308155,0.0003397072,0.00004108213,0.00003418852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003561399,0.0001476467,0.004593923,0.0001597586,0.0006639974,0.000002805575,0.0002900087,0.0001596259,0.9877592,0.00008762274,0.00001756336,0.00576175],"study_design_scores_gemma":[0.0006242217,0.0003891859,0.03779278,0.00005789664,0.0001166168,0.000001086407,0.00001917077,0.00005402811,0.9605291,0.0001228119,0.0002143248,0.00007870646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830864,0.0159308,0.00005335341,0.00008676959,0.00003631706,0.0004743641,0.00008056191,0.000001672684,0.0002497517],"genre_scores_gemma":[0.9908565,0.008579103,0.00008481551,0.0002984984,0.00001181511,0.0001127447,0.000007981069,0.00001950723,0.00002901245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03319886,"threshold_uncertainty_score":0.3529495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01955027477734175,"score_gpt":0.2508242462791802,"score_spread":0.2312739715018385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}