{"id":"W2324813092","doi":"10.1101/pdb.top087593","title":"High-Throughput Microscopy-Based Screening in <i>Saccharomyces cerevisiae</i>","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Saccharomyces cerevisiae; Budding yeast; Computational biology; Yeast; DNA microarray; Model organism; Genome; Throughput; Fluorescence microscope; Biology; Computer science; Genetics; Gene; Gene expression; Fluorescence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003679665,0.0002170885,0.0002130384,0.00008300778,0.00007699218,0.00006818197,0.000436042,0.0001609362,0.00006064083],"category_scores_gemma":[0.0001126844,0.0001693213,0.00008887249,0.000163858,0.00009941656,0.000007972915,0.0002195944,0.0001254793,0.0000588978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002698046,"about_ca_system_score_gemma":0.000172655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004787954,"about_ca_topic_score_gemma":0.00002211533,"domain_scores_codex":[0.9982707,0.00009241738,0.0003067352,0.0005633132,0.0002448965,0.000521965],"domain_scores_gemma":[0.9990749,0.00003081418,0.0000847394,0.0005776312,0.00009476596,0.0001371837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001800326,0.0000751767,0.02854336,0.00007921118,0.00001336289,0.000009097314,0.000002009163,0.00004092284,0.9695541,0.0003034782,0.0002843713,0.0009148972],"study_design_scores_gemma":[0.001753008,0.0002493167,0.007995299,0.0003884312,0.000002581384,3.499499e-7,0.000001395697,0.00002593859,0.9033719,0.000009993114,0.08595809,0.0002436832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9416009,0.0005796029,0.01570091,0.001193241,0.0001160836,0.04043742,0.0000679181,0.00007510864,0.000228782],"genre_scores_gemma":[0.9581406,0.00003058321,0.01018867,0.0002295758,0.0002710596,0.03075249,0.000002374694,0.0000568646,0.0003277594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08567372,"threshold_uncertainty_score":0.6904722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01992756795820047,"score_gpt":0.3030972948673913,"score_spread":0.2831697269091908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}