{"id":"W2325054384","doi":"10.1158/0008-5472.sabcs-09-1083","title":"Change in Receptor Status in Locally Advanced Breast Cancer Patients after Treatment with Neoadjuvant Therapy (NAT).","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Breast cancer; Mastectomy; Neoadjuvant therapy; Oncology; Internal medicine; Cancer; Progesterone receptor; Stage (stratigraphy); Biopsy; Hormonal therapy; Metastatic breast cancer; Breast-conserving surgery; Adjuvant therapy; Prospective cohort study; Estrogen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003874198,0.0001030164,0.0003024839,0.0004228507,0.0001850205,0.0003289614,0.000232768,0.0002543564,0.001041702],"category_scores_gemma":[0.001546606,0.00009808847,0.0001602937,0.0007541479,0.0001911686,0.0002520096,0.0001642758,0.0002392273,0.0002142848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005827872,"about_ca_system_score_gemma":0.0002080625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002216091,"about_ca_topic_score_gemma":0.004063759,"domain_scores_codex":[0.9997452,0.000055036,0.00004130415,0.00004962599,0.00007482662,0.00003396884],"domain_scores_gemma":[0.9988201,0.0002500702,0.0006276802,0.00003978256,0.00012179,0.0001404031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006029141,0.00003384326,0.9952981,0.00002571503,0.00001214945,0.0002179835,0.00004739313,0.00003226763,0.0007181402,0.00000327186,0.00008937206,0.002918924],"study_design_scores_gemma":[0.000009704075,0.0003147863,0.9984365,0.000003541661,0.0000115115,0.0007013828,0.00006075322,0.00006392429,0.0001710445,0.00000355747,0.0002207068,0.000002657489],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998786,0.0005730637,0.00002371483,0.00002328632,0.000003423118,0.00001160996,0.0002757615,0.000002697921,0.0003004316],"genre_scores_gemma":[0.9991732,0.0001472769,0.00007532119,0.00002290927,0.000005418892,0.00001381541,0.0004219748,8.357986e-7,0.0001392943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002216091,"threshold_uncertainty_score":0.004406393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02812885234314256,"score_gpt":0.3574429687119552,"score_spread":0.3293141163688126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}