{"id":"W2325233772","doi":"10.1021/bi101316y","title":"Multiple, Distributed Interactions of μ-Conotoxin PIIIA Associated with Broad Targeting among Voltage-Gated Sodium Channels","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Sodium channel; Chemistry; Toxin; Biophysics; Arginine; Biochemistry; Stereochemistry; Sodium; Amino acid; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717788,0.0002604912,0.0004571301,0.0002457235,0.0002210511,0.0004555933,0.0003485669,0.0003409048,0.000846408],"category_scores_gemma":[0.0002731099,0.0001628968,0.0003134126,0.0002932708,0.00024014,0.0003225752,0.0005585465,0.0009540961,0.0003832116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006153774,"about_ca_system_score_gemma":0.0003154757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004886306,"about_ca_topic_score_gemma":0.0006743927,"domain_scores_codex":[0.9996645,0.00002774523,0.00001769777,0.00007562512,0.0001060983,0.0001082533],"domain_scores_gemma":[0.9998568,0.00001596322,0.00002628443,0.00002350582,0.00002152166,0.00005574463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000793172,0.00003027843,0.0002532978,0.00001748015,0.000008945995,0.00005401932,0.000004656328,0.0001477686,0.9972736,0.00007069272,0.00003976781,0.002020263],"study_design_scores_gemma":[0.00004472794,0.0007158488,0.0119588,0.00001152982,0.00005937187,0.0006191495,0.00003979066,0.004963063,0.9791047,0.0001839647,0.002291191,0.000007826067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914477,0.001649778,0.004939621,0.00008468266,0.00003004371,0.00004231277,0.00009202066,0.00007432805,0.001639553],"genre_scores_gemma":[0.9955141,0.0007288237,0.002291949,0.00008383739,0.00001409318,0.0000430867,0.0001612707,0.00001369807,0.001149109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000846408,"threshold_uncertainty_score":0.004464865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007061434828100968,"score_gpt":0.221724347602288,"score_spread":0.214662912774187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}