{"id":"W2325233772","doi":"10.1021/bi101316y","title":"Multiple, Distributed Interactions of μ-Conotoxin PIIIA Associated with Broad Targeting among Voltage-Gated Sodium Channels","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Sodium channel; Chemistry; Toxin; Biophysics; Arginine; Biochemistry; Stereochemistry; Sodium; Amino acid; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001556799,0.0002094939,0.0001763152,0.00004030213,0.0001174228,0.0000284477,0.0001513453,0.0003018529,0.0001043653],"category_scores_gemma":[0.0006183853,0.00019767,0.0001018772,0.0001830911,0.0001743347,0.00001018255,0.00006707467,0.0002419185,0.000004354846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002263583,"about_ca_system_score_gemma":0.00007522261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003528201,"about_ca_topic_score_gemma":0.00004337149,"domain_scores_codex":[0.9988986,0.00002272178,0.0003056804,0.0003682421,0.0001508271,0.0002539447],"domain_scores_gemma":[0.9989371,0.00002896383,0.0002842596,0.0002952927,0.0003368183,0.0001175784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001224665,0.0001258024,0.01568097,0.00001945409,0.00008459329,0.000001386643,0.00002476022,0.0001643933,0.9804704,0.000003105803,0.003152527,0.0001501424],"study_design_scores_gemma":[0.0009093229,0.00006548112,0.00703045,0.0000355374,0.00002355788,0.000006852054,0.0001232396,0.004038948,0.9844661,0.00000486385,0.003048083,0.0002475927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944568,0.00002475481,0.004109095,0.00005334834,0.0006073228,0.0001625113,0.0001638759,0.00004981104,0.0003724233],"genre_scores_gemma":[0.9937515,0.00000392184,0.0001449526,0.00003047525,0.0004571412,0.00002354446,0.004005022,0.00002924773,0.001554151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008650514,"threshold_uncertainty_score":0.8060749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007061434828100968,"score_gpt":0.221724347602288,"score_spread":0.214662912774187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}