{"id":"W2325246333","doi":"10.1038/cgt.2011.62","title":"Fibroblast growth factor and ornithine decarboxylase 5′UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN−/− transgenic mice","year":2011,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Terry Fox Foundation","keywords":"PTEN; Ornithine decarboxylase; Prostate cancer; Cancer research; Prostate; Genetically modified mouse; Cancer; Transgene; Biology; Chemistry; Medicine; Internal medicine; Apoptosis; Enzyme; Gene; PI3K/AKT/mTOR pathway; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005573456,0.0001658521,0.0001948989,0.00006386505,0.0000356214,0.000008288486,0.0001048822,0.00006422321,0.00003425582],"category_scores_gemma":[0.000001478523,0.0001419388,0.00002640589,0.000101904,0.00009302574,0.00001064873,0.00003661352,0.0000757948,1.634375e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009892646,"about_ca_system_score_gemma":0.00007088406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008486731,"about_ca_topic_score_gemma":0.0006591332,"domain_scores_codex":[0.9991108,0.00004257043,0.0002361796,0.0003316418,0.00006235492,0.0002164599],"domain_scores_gemma":[0.9996356,0.000003238541,0.00009346063,0.000157947,0.00004020609,0.00006952778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003386885,0.00007924201,0.009331923,0.00004929816,0.00001508487,4.753463e-7,0.001230234,0.00001407553,0.9874594,0.000002717046,0.00002225924,0.001456622],"study_design_scores_gemma":[0.001711638,0.0001029497,0.04135804,0.00006369358,0.000005759117,7.335419e-7,0.00004577909,0.000008076042,0.9562327,0.00008297118,0.0002291257,0.0001584915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928174,0.006328464,0.00002194733,0.00001841444,0.00003074649,0.0004896935,0.000260317,0.000005403451,0.00002761841],"genre_scores_gemma":[0.987406,0.01186908,0.0001632701,0.00004138165,0.00005822037,0.0002756218,0.00003586931,0.00002457579,0.0001259766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03202612,"threshold_uncertainty_score":0.5788096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01715190181848626,"score_gpt":0.2538910189569403,"score_spread":0.2367391171384541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}