{"id":"W2325274793","doi":"10.1089/10430340050016120","title":"Phenotypic Correction of Feline Lipoprotein Lipase Deficiency by Adenoviral Gene Transfer","year":2000,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; University of British Columbia","keywords":"Lipoprotein lipase; Biology; Molecular biology; Adipose tissue; Viral vector; Genetic enhancement; Enzyme replacement therapy; Spleen; Endocrinology; Internal medicine; Gene; Immunology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003976416,0.0003450074,0.0004060235,0.0004439415,0.0001760777,0.0003789038,0.0003705676,0.0004895469,0.001523769],"category_scores_gemma":[0.0004731303,0.0001494219,0.0002905661,0.0001354174,0.0003419472,0.0002482071,0.0002964083,0.0006908469,0.0002889666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000423535,"about_ca_system_score_gemma":0.0003079494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130081,"about_ca_topic_score_gemma":0.001398407,"domain_scores_codex":[0.999705,0.00005812815,0.00003761808,0.00006578583,0.00006264877,0.00007069289],"domain_scores_gemma":[0.9996723,0.00007843045,0.0000905077,0.00005192283,0.0000303308,0.00007656854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002240822,0.0001039588,0.0006434426,0.00006564949,0.00001445118,0.0004139231,0.00004313223,0.00019227,0.9932262,0.0003033237,0.0001170092,0.004652412],"study_design_scores_gemma":[0.0001283514,0.00218795,0.01201247,0.00004509059,0.00006107124,0.004883617,0.0001351006,0.003827416,0.963171,0.0001656852,0.0133609,0.00002120987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900838,0.0006695039,0.0064961,0.0002212596,0.00006497872,0.0001888367,0.0005929202,0.0002378539,0.00144464],"genre_scores_gemma":[0.9889814,0.0006820678,0.005269865,0.00009810163,0.00001969973,0.0001469771,0.0007932493,0.00005315763,0.003955578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001523769,"threshold_uncertainty_score":0.005097508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591728524933089,"score_gpt":0.2559566075478948,"score_spread":0.240039322298564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}