{"id":"W2325675836","doi":"10.1111/xen.12222","title":"First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes – Chapter 1: update on national regulatory frameworks pertinent to clinical islet xenotransplantation","year":2016,"lang":"en","type":"article","venue":"Xenotransplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"U.S. Food and Drug Administration","keywords":"Xenotransplantation; Scale (ratio); Economic shortage; Political science; Medicine; Transplantation; Geography; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03354441,0.001235281,0.002367639,0.005291293,0.001334583,0.005718752,0.005036247,0.01161243,0.009769128],"category_scores_gemma":[0.06656741,0.001147634,0.00264816,0.004108641,0.00187626,0.004709474,0.004312953,0.0134557,0.01114492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003916901,"about_ca_system_score_gemma":0.01763402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008084949,"about_ca_topic_score_gemma":0.01303086,"domain_scores_codex":[0.978663,0.005208498,0.004800282,0.0008427157,0.009470806,0.001014645],"domain_scores_gemma":[0.9281724,0.02087319,0.007724316,0.001841584,0.03758256,0.003805781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000041979,0.00006941435,0.0002991541,0.00139984,0.00002315471,0.0001264037,0.0001796254,0.0001023357,0.0003902668,0.002424793,0.9235247,0.0714182],"study_design_scores_gemma":[0.00002826569,0.0000354949,0.0008810771,0.003268603,0.00002975787,0.0002115054,0.00008061442,0.00003886013,0.0001481713,0.001169048,0.9940799,0.00002871582],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.001824615,0.2574039,0.01115795,0.4249128,0.1822305,0.001763281,0.008116924,0.0009443048,0.1116457],"genre_scores_gemma":[0.00956189,0.3502299,0.04088584,0.3893177,0.1015526,0.003930872,0.0252127,0.001073057,0.07823545],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.03354441,"threshold_uncertainty_score":0.1774019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1138750563179217,"score_gpt":0.4199663275896918,"score_spread":0.30609127127177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}