{"id":"W2325833230","doi":"10.1038/sj.cgt.7700116","title":"Adenoviral transfer of xenogeneic MHC class I gene results in loss of tumorigenicity and inhibition of tumor growth","year":2000,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Medical Research Council; Saskatchewan Cancer Agency; University of Saskatchewan; University of Alabama at Birmingham","keywords":"Biology; Major histocompatibility complex; Immune system; MHC class I; Antigen; Immunology; Cancer research; Transfection; Tumor antigen; Cell culture; Immunotherapy; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000219586,0.00054954,0.0004135531,0.0006119346,0.0002841395,0.0004562517,0.0003838785,0.0004023024,0.002121272],"category_scores_gemma":[0.0002166583,0.0002392011,0.0003714168,0.0003983978,0.0004827581,0.0002833782,0.0002940427,0.0009481903,0.000546037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004504118,"about_ca_system_score_gemma":0.000480772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001599169,"about_ca_topic_score_gemma":0.001438141,"domain_scores_codex":[0.9997258,0.00003675036,0.00002564199,0.00005121002,0.00009138345,0.00006918454],"domain_scores_gemma":[0.9996814,0.000103259,0.00006779694,0.00005795308,0.00001616032,0.00007337703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001617989,0.00006971255,0.0001404323,0.00002073277,0.000006566564,0.00006908664,0.00001338032,0.00009713091,0.9981093,0.0004530646,0.0000565095,0.0008022063],"study_design_scores_gemma":[0.00001662634,0.0001815415,0.0009949426,0.000002272281,0.00001080919,0.000250478,0.00001434341,0.0007290171,0.9966199,0.00006262792,0.00111432,0.000002953684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865767,0.002096112,0.005301308,0.000170152,0.0001332189,0.00005556647,0.0009231645,0.0003472239,0.00439653],"genre_scores_gemma":[0.992968,0.0006432834,0.001355216,0.00003330546,0.00001588767,0.00003797035,0.0007727321,0.00004626872,0.004127368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002121272,"threshold_uncertainty_score":0.00709635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718763236942778,"score_gpt":0.2828939649167775,"score_spread":0.2657063325473497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}