{"id":"W2325839971","doi":"10.1242/dev.108274","title":"A regulatory network controls nephrocan expression and midgut patterning","year":2014,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; McGill University; University of British Columbia; BC Cancer Agency","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institute of General Medical Sciences; McGill University","keywords":"Biology; Endoderm; Midgut; Nodal signaling; NODAL; Cell biology; Retinoic acid; Enhancer; Regulation of gene expression; Signal transduction; Embryonic stem cell; Gene expression; Embryo; Gene; Genetics; Embryogenesis; Gastrulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002605608,0.00009287957,0.00008642083,0.00001486875,0.0001011866,0.00001965199,0.00005237213,0.00007506582,0.000007298288],"category_scores_gemma":[0.0000242882,0.00008593345,0.00001654925,0.00002096927,0.000019599,0.000001549373,0.00007569054,0.00003581248,0.000003856848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007554296,"about_ca_system_score_gemma":0.00002861383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001633296,"about_ca_topic_score_gemma":0.000009124102,"domain_scores_codex":[0.9993489,0.00004634422,0.0001459944,0.0002099936,0.00008792736,0.0001608369],"domain_scores_gemma":[0.9996989,0.0000106696,0.0000568,0.0001390478,0.00002790031,0.00006663393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002538691,0.00001212775,0.03840971,0.00001234182,0.0000192008,4.803458e-7,0.0001225571,0.0002233959,0.9050577,0.00005332381,0.0005995728,0.05546422],"study_design_scores_gemma":[0.0005331442,0.00006871983,0.1808776,0.00003599602,0.000004824151,0.000001122449,0.00001329988,0.0001450362,0.4354419,0.0001434738,0.3825407,0.000194217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758456,0.001023357,0.0221538,0.00004083072,0.00009135171,0.00008728258,4.463732e-7,0.000008631571,0.0007487047],"genre_scores_gemma":[0.9908833,0.00005644061,0.008239085,0.0002614447,0.0002227902,0.00001825047,0.00004667172,0.00001225421,0.0002597946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4696158,"threshold_uncertainty_score":0.3504264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006265993734722709,"score_gpt":0.2113335741619861,"score_spread":0.2050675804272634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}