{"id":"W2325839971","doi":"10.1242/dev.108274","title":"A regulatory network controls nephrocan expression and midgut patterning","year":2014,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; McGill University; University of British Columbia; BC Cancer Agency","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institute of General Medical Sciences; McGill University","keywords":"Biology; Endoderm; Midgut; Nodal signaling; NODAL; Cell biology; Retinoic acid; Enhancer; Regulation of gene expression; Signal transduction; Embryonic stem cell; Gene expression; Embryo; Gene; Genetics; Embryogenesis; Gastrulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007313534,0.0002181154,0.0001658283,0.0002035065,0.0001633611,0.0002740575,0.0001627861,0.000149364,0.0006780628],"category_scores_gemma":[0.00009844379,0.000194004,0.0001434088,0.00009082162,0.0002734202,0.00021966,0.0002781627,0.0002383451,0.0002547415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003363773,"about_ca_system_score_gemma":0.0002989609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006198133,"about_ca_topic_score_gemma":0.001472646,"domain_scores_codex":[0.9998893,0.00001151482,0.00000579451,0.00004385397,0.00002819633,0.00002132032],"domain_scores_gemma":[0.999894,0.00001041521,0.00004253396,0.000009030725,0.00001387195,0.00003015994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000035774,0.000002609783,0.0005931631,0.000008540712,0.000002017973,0.00003419665,0.000009348621,0.00004228829,0.9983445,0.0002507775,0.000007286243,0.0006693244],"study_design_scores_gemma":[0.00001588044,0.00009373533,0.05618982,0.0000128702,0.00002711699,0.0004008987,0.00007372428,0.002194926,0.9375215,0.0003649209,0.003095388,0.000009184339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921567,0.001384942,0.004052004,0.00005379887,0.00001056634,0.00001026587,0.0001979234,0.00006336167,0.002070391],"genre_scores_gemma":[0.9948305,0.0005704394,0.002033747,0.00001994035,0.000004828088,0.00001417805,0.0002475723,0.00001436857,0.00226435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006780628,"threshold_uncertainty_score":0.002440631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006265993734722709,"score_gpt":0.2113335741619861,"score_spread":0.2050675804272634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}