{"id":"W2325916270","doi":"10.1158/1538-7445.am2012-1488","title":"Abstract 1488: Role of niche requirements in transient leukemia of Down syndrome","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Haematopoiesis; GATA1; Bone marrow; Stromal cell; Leukemia; Trisomy; Fetus; Extramedullary hematopoiesis; Stem cell; Cancer research; CD34; Myeloid leukemia; Myeloid; Biology; Pathology; Medicine; Immunology; Cell biology; Genetics; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007582431,0.0001841652,0.0001425408,0.0002083107,0.0001116085,0.0002511624,0.0001711085,0.0002042473,0.002560145],"category_scores_gemma":[0.0001037926,0.00009039962,0.0001055204,0.00009556689,0.0001702332,0.0001556291,0.0003085421,0.0002295288,0.0004386331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00015449,"about_ca_system_score_gemma":0.0001311997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004693877,"about_ca_topic_score_gemma":0.0004338175,"domain_scores_codex":[0.9999337,0.000009552718,0.000005493485,0.00001232284,0.00001899834,0.00002001416],"domain_scores_gemma":[0.9999058,0.00002100594,0.00002044632,0.000006671968,0.000008891839,0.00003704156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001309752,0.000007960462,0.001653429,0.0000413924,0.000001870645,0.0003700989,0.00001583432,0.00004052268,0.9954639,0.0001586541,0.00004469234,0.0020706],"study_design_scores_gemma":[0.00005105022,0.0006283762,0.1221496,0.00003645849,0.00003138234,0.008331161,0.000223211,0.002369331,0.855136,0.0002883459,0.0107437,0.00001133722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952433,0.001594634,0.0009858204,0.00005693223,0.00001085806,0.000008196094,0.0003601946,0.00003435501,0.001705707],"genre_scores_gemma":[0.9972825,0.0004538054,0.0006369961,0.00002084437,0.00000544768,0.00001225304,0.0003823718,0.000008933065,0.001196781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002560145,"threshold_uncertainty_score":0.008564532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.090553124337799,"score_gpt":0.4201862607957564,"score_spread":0.3296331364579574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}