{"id":"W2326177472","doi":"10.1097/tp.0b013e31821eabab","title":"The Risk to Human Islet Cell Transplant Recipients of Acquiring Variant Creutzfeldt-Jakob Disease: A Provisional Quantitative Risk Assessment","year":2011,"lang":"en","type":"letter","venue":"Transplantation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; Robarts Clinical Trials; Translational Research in Oncology; Institute of Population and Public Health; University of Ottawa; Public Health Agency of Canada","funders":"","keywords":"Islet; Transplantation; Collagenase; Medicine; Xenotransplantation; Diabetes mellitus; Surgery; Biology; Enzyme; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002629315,0.0006616098,0.0002689084,0.001252523,0.0002860059,0.0007463621,0.0004418256,0.0008309329,0.001651591],"category_scores_gemma":[0.004318707,0.0001417547,0.0003723588,0.0005789453,0.0004434566,0.0005367474,0.0008879013,0.0004076036,0.0003820176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004031013,"about_ca_system_score_gemma":0.0002047037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003114099,"about_ca_topic_score_gemma":0.0002960421,"domain_scores_codex":[0.998571,0.0006678023,0.0000868991,0.0001106558,0.0005167754,0.00004682962],"domain_scores_gemma":[0.9978072,0.0007086532,0.0009593177,0.0001427998,0.0002308609,0.0001511479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.004733813,0.0006078529,0.9082747,0.0002585199,0.0002746505,0.0006390117,0.0003162496,0.002485179,0.005845927,0.0014861,0.001159203,0.07391874],"study_design_scores_gemma":[0.0001155522,0.01405226,0.9388707,0.00018517,0.0008238917,0.008367539,0.0007983177,0.01386942,0.008890714,0.003073604,0.01083691,0.0001159805],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677085,0.004039497,0.01927606,0.0004785981,0.00004000005,0.0003268106,0.001424934,0.000107574,0.006598055],"genre_scores_gemma":[0.9923274,0.0008574925,0.005328013,0.000124853,0.00004604112,0.0001030804,0.0004594401,0.00000700124,0.0007466433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002629315,"threshold_uncertainty_score":0.01390529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01583763415187397,"score_gpt":0.2844061909914294,"score_spread":0.2685685568395555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}