{"id":"W2326408693","doi":"10.1021/es502054h","title":"Functionality of Aryl Hydrocarbon Receptors (AhR1 and AhR2) of White Sturgeon (<i>Acipenser transmontanus</i>) and Implications for the Risk Assessment of Dioxin-like Compounds","year":2014,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Environment and Climate Change Canada; Ontario Genomics; University of Saskatchewan","funders":"","keywords":"Sturgeon; Aryl hydrocarbon receptor; Dibenzofuran; Chemistry; EC50; Zoology; Biology; Internal medicine; Toxicology; Fishery; Fish <Actinopterygii>; In vitro; Gene; Biochemistry; Medicine; Organic chemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561092,0.000348967,0.0001958664,0.0003446502,0.0001507266,0.0002843338,0.0001641488,0.0003448082,0.00127197],"category_scores_gemma":[0.0001727149,0.0001394966,0.0005208032,0.0002162333,0.0001935347,0.0001882386,0.0002309725,0.0003356037,0.0002831403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003510779,"about_ca_system_score_gemma":0.0001919961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002210403,"about_ca_topic_score_gemma":0.003847184,"domain_scores_codex":[0.9997668,0.00002881399,0.00002372076,0.00006278758,0.00006563612,0.00005220306],"domain_scores_gemma":[0.9998796,0.00001866367,0.00004696403,0.000009095584,0.00002419021,0.00002148786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006558017,0.00001369021,0.002329942,0.00002930874,0.000008094506,0.00002271746,0.00001854348,0.00005058893,0.9965578,0.00003622254,0.0000204464,0.0008470489],"study_design_scores_gemma":[0.0000270043,0.001875557,0.3042983,0.00002289206,0.0001645107,0.0009614485,0.0003816885,0.001579951,0.686268,0.0001542076,0.004224089,0.00004239546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965634,0.0009814951,0.0008454831,0.0001077696,0.00001818678,0.00001181467,0.0003866873,0.00003252459,0.001052706],"genre_scores_gemma":[0.9942173,0.000840823,0.001082721,0.000125559,0.000008262602,0.00002059931,0.001354677,0.000008319437,0.002341772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002210403,"threshold_uncertainty_score":0.004395008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006300921444720942,"score_gpt":0.2301036971848216,"score_spread":0.2238027757401007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}