{"id":"W2326443520","doi":"10.1021/bm5000696","title":"Early Fibrillin-1 Assembly Monitored through a Modifiable Recombinant Cell Approach","year":2014,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Fibrillin; Microfibril; Fibronectin; Recombinant DNA; Cell biology; Chemistry; Extracellular matrix; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004353099,0.000567459,0.0003031046,0.0002966597,0.0001969336,0.0003668297,0.0004446493,0.0005009231,0.0009833346],"category_scores_gemma":[0.0002516386,0.0002579412,0.000299132,0.0001826823,0.0002986942,0.0002524348,0.0003491803,0.001003909,0.0007522115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004879704,"about_ca_system_score_gemma":0.0001843606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006169362,"about_ca_topic_score_gemma":0.0007338567,"domain_scores_codex":[0.9996326,0.00007160653,0.00004134194,0.0001095505,0.00009857446,0.00004633731],"domain_scores_gemma":[0.9997215,0.00009190096,0.00006981363,0.00005491411,0.00003514999,0.00002669723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001062126,0.000005677711,0.00001156573,0.00000737179,0.000001020295,0.000005902614,0.000006084433,0.00001453399,0.9997103,0.00003468345,0.000008142197,0.0001840975],"study_design_scores_gemma":[0.000005655843,0.0000552932,0.0002175385,0.000001755845,0.000006710077,0.00004069012,0.000004038458,0.0007699205,0.99778,0.00001576144,0.001099026,0.000003599066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8780507,0.002287123,0.1139895,0.0002063133,0.0001501842,0.0003562897,0.001406642,0.000577706,0.002975374],"genre_scores_gemma":[0.8908073,0.001854996,0.09660359,0.0001198609,0.00003860928,0.00031369,0.002494501,0.0002259103,0.007541629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009833346,"threshold_uncertainty_score":0.003540456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01493000041104546,"score_gpt":0.2626946093533398,"score_spread":0.2477646089422944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}