{"id":"W2326444048","doi":"10.1016/j.bbrep.2016.04.002","title":"Expression and purification of the full murine NPM2 and study of its interaction with protamines and histones","year":2016,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Genome British Columbia; Genome Canada","keywords":"Histone; Pentamer; Histone octamer; Chromatin; Xenopus; Molecular biology; Biology; Protamine; Chemistry; Cell biology; Histone H2B; Genetics; Biochemistry; Nucleosome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001650159,0.0002835666,0.0001593058,0.0001836872,0.000195385,0.0002131374,0.000244357,0.0001903178,0.0005236217],"category_scores_gemma":[0.0001410682,0.000126979,0.0001852441,0.0002360028,0.0001543362,0.0001359746,0.0002100426,0.0003448361,0.0004070516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000399421,"about_ca_system_score_gemma":0.0001542565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008732087,"about_ca_topic_score_gemma":0.001162584,"domain_scores_codex":[0.9999163,0.00001372027,0.000008476144,0.00002404442,0.00002409497,0.00001334342],"domain_scores_gemma":[0.999925,0.00001467434,0.00001523775,0.00001379581,0.00001084974,0.00002041519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004523657,0.0000140919,0.0002157227,0.00002553252,0.000002856644,0.00005549482,0.00001662541,0.00005303424,0.9988241,0.0001475659,0.00003447743,0.0005652253],"study_design_scores_gemma":[0.00002140401,0.0001003933,0.01081911,0.00001134861,0.00001302742,0.0006268916,0.00003725592,0.001483843,0.974585,0.000101476,0.01219373,0.000006456763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884073,0.001056311,0.007103513,0.0001552656,0.0000243137,0.00004432169,0.001712609,0.00005748895,0.001438893],"genre_scores_gemma":[0.9609172,0.001121297,0.02123019,0.00008890937,0.00002889401,0.0001298904,0.01043694,0.00007240823,0.00597431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008732087,"threshold_uncertainty_score":0.002898037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00558989821018973,"score_gpt":0.2131200909331669,"score_spread":0.2075301927229772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}