{"id":"W2326819017","doi":"10.1021/ac503816u","title":"Metabolic Profiling of Bile Acids in Human and Mouse Blood by LC–MS/MS in Combination with Phospholipid-Depletion Solid-Phase Extraction","year":2014,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Victoria","funders":"Terry Fox Research Institute; Canadian Institutes of Health Research; Genome British Columbia; Genome Canada","keywords":"Chemistry; Solid phase extraction; Phospholipid; Chromatography; Profiling (computer programming); Lipidomics; Extraction (chemistry); Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002548583,0.0001319831,0.0003460735,0.00006228583,0.0000259566,0.000008945397,0.00004305179,0.0001386909,0.00005369351],"category_scores_gemma":[0.00003634288,0.0001109322,0.00003535851,0.0002204859,0.00008435633,0.00006933259,0.000006991248,0.000233283,5.786366e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002518811,"about_ca_system_score_gemma":0.00002733079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005613993,"about_ca_topic_score_gemma":0.00002165122,"domain_scores_codex":[0.9989983,0.00001349265,0.0003252572,0.000255233,0.000224948,0.0001827855],"domain_scores_gemma":[0.9995796,0.00002251404,0.00008516425,0.0001624068,0.00005512289,0.00009521278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001920226,0.001073781,0.03169567,0.0002952571,0.00002978246,0.00001287196,0.00004978499,0.000009322184,0.9660791,0.0003898321,0.000009029748,0.0001635925],"study_design_scores_gemma":[0.005601312,0.0001777936,0.005200431,0.0001322171,0.0001740318,0.000008798026,0.00008725243,0.003137793,0.9850937,0.0001354044,0.000124706,0.000126626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975954,0.0001101075,0.000948193,0.0001005676,0.000008178259,0.0001546861,0.000005928805,0.00002291064,0.00105399],"genre_scores_gemma":[0.9989886,0.00004208031,0.0002455117,0.00002517771,0.00003412688,0.00001556567,0.0001443961,0.0000171433,0.0004874414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02649524,"threshold_uncertainty_score":0.4523684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008153140141982483,"score_gpt":0.290465209737543,"score_spread":0.2823120695955605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}