{"id":"W2326830432","doi":"10.1097/00004872-200402001-00476","title":"ENDOTHELIN-1 REGULATES MAP KINASES THROUGH MITOCHONDRIAL-DERIVED REACTIVE OXYGEN SPECIES, WHEREAS ANGIOTENSIN II EFFECTS ARE MEDIATED VIA NADPH OXIDASE-DERIVED SUPEROXIDE IN HUMAN VASCULAR SMOOTH MUSCLE CELLS","year":2004,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"NADPH oxidase; Reactive oxygen species; Medicine; Superoxide; Angiotensin II; Vascular smooth muscle; Endothelin 1; Oxidase test; Cell biology; Endocrinology; Smooth muscle; Internal medicine; Biochemistry; Oxidative stress; Enzyme; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466696,0.000244126,0.0001488371,0.0001400078,0.0002005771,0.0002685945,0.0001341926,0.0001822693,0.001478796],"category_scores_gemma":[0.0001503134,0.0001277281,0.0001691944,0.0001347956,0.000141791,0.0002867846,0.0001434701,0.0004526469,0.0002904493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002270098,"about_ca_system_score_gemma":0.0001662603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006182318,"about_ca_topic_score_gemma":0.001155104,"domain_scores_codex":[0.9998351,0.0000341165,0.00001042869,0.00002309151,0.00003035033,0.00006680973],"domain_scores_gemma":[0.9999005,0.00001889509,0.00002044586,0.00001483772,0.00001573813,0.00002957594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007093169,0.00006242959,0.0005950192,0.00003779324,0.000005778235,0.0001094293,0.00006430777,0.00002817789,0.9966371,0.0001677763,0.000082089,0.001500809],"study_design_scores_gemma":[0.0001799851,0.0009523102,0.1105849,0.00001895447,0.00004214511,0.0008111247,0.0002639033,0.0008818498,0.8829478,0.0003496973,0.00295568,0.00001166553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951975,0.002411472,0.000952475,0.0001798303,0.00006710596,0.000008890413,0.0001573005,0.0000176353,0.001007801],"genre_scores_gemma":[0.9954361,0.001231398,0.0004424751,0.00004997796,0.00003025924,0.00001772553,0.0003416081,0.000004207196,0.002446197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001478796,"threshold_uncertainty_score":0.004947066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617234440959905,"score_gpt":0.2091460428028347,"score_spread":0.1929736983932357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}