{"id":"W2326971524","doi":"10.1158/1538-7445.am2012-5420","title":"Abstract 5420: The effect of folate deficiency on chemosensitivity of colon cancer cells to 5-Fluorouracil","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Thymidylate synthase; Colorectal cancer; Cell growth; Cell culture; Intracellular; Cancer cell; Biology; Biochemistry; Cancer research; Molecular biology; Cancer; Fluorouracil; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001377827,0.0003568728,0.0003758305,0.0002801271,0.0001866971,0.0002683459,0.0002401128,0.0004856822,0.003530241],"category_scores_gemma":[0.0002090429,0.0001443967,0.0002728743,0.0002806502,0.0001443938,0.0001562923,0.0001703788,0.0004869004,0.0006034108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003263387,"about_ca_system_score_gemma":0.0002476542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002936998,"about_ca_topic_score_gemma":0.002214461,"domain_scores_codex":[0.9998159,0.00004393908,0.00002823837,0.00002851704,0.0000458191,0.00003766608],"domain_scores_gemma":[0.9998134,0.0000595485,0.00002837603,0.00002279993,0.0000337741,0.00004221469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009857269,0.00008722892,0.0005060764,0.00007224625,0.00001141644,0.00008720515,0.00002352419,0.0000552483,0.9962505,0.00002776886,0.0001645771,0.001728558],"study_design_scores_gemma":[0.00006630306,0.002738912,0.01589856,0.00001834621,0.00004192127,0.0004615945,0.00005842298,0.000646471,0.9763727,0.00002140584,0.00366706,0.000008217612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935261,0.003045946,0.0003700605,0.0001607376,0.00004591439,0.00002739416,0.0009651764,0.00004523408,0.001813453],"genre_scores_gemma":[0.9912656,0.001308123,0.0007402375,0.00008143031,0.00001566944,0.00004487554,0.002376393,0.00001404498,0.004153528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003530241,"threshold_uncertainty_score":0.01180983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07494627721796471,"score_gpt":0.4398807192616934,"score_spread":0.3649344420437287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}